Quantitative changes in cytological molecular markers during primary medical treatment of breast cancer: A pilot study

To quantify the changes in biological molecular markers during primary medical treatment in patients with operable breast cancer and to assess their possible relationship with response to treatment. The treatment group consisted of 31 patients with operable breast carcinomas, median age 57 years (ra...

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Bibliographic Details
Published in:	Breast cancer research and treatment Vol. 53; no. 1; pp. 51 - 59
Main Authors:	Makris, A., Powles, T.J., Allred, D.C., Ashley, S.E., Trott, P.A., Ormerod, M.G., Dowsett, M.
Format:	Journal Article
Language:	English
Published:	Dordrecht Springer 01.01.1999 Springer Nature B.V
Subjects:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Biomarkers, Tumor - metabolism Biopsy, Needle Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Cancer research Cancer therapies Chemotherapy, Adjuvant Female Flow Cytometry Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Ki-67 Antigen - metabolism Mammary gland diseases Medical sciences Methotrexate - administration & dosage Middle Aged Mitoxantrone - administration & dosage Pilot Projects Ploidies Preoperative Care Prospective Studies Proto-Oncogene Proteins c-bcl-2 - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Tamoxifen - administration & dosage Treatment Outcome Tumor Suppressor Protein p53 - metabolism Tumors Human Ploidy Immunocytochemistry Estrogen Tumoral marker Malignant tumor Neoadjuvant treatment Mammary gland diseases TP53 Gene Cohort study Female Mammary gland Progesterone Onc gene Hormonal receptor
ISSN:	0167-6806, 1573-7217
Online Access:	Get full text
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