Subgroups from regression trees with adjustment for prognostic effects and postselection inference

Identification of subgroups with differential treatment effects in randomized trials is attracting much attention. Many methods use regression tree algorithms. This article addresses 2 important questions arising from the subgroups: how to ensure that treatment effects in subgroups are not confounde...

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Bibliographic Details
Published in:	Statistics in medicine Vol. 38; no. 4; pp. 545 - 557
Main Authors:	Loh, Wei‐Yin, Man, Michael, Wang, Shuaicheng
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 20.02.2019
Subjects:	Algorithms bootstrap Bootstrap method Breast cancer Clinical trials differential treatment effect Humans Kaplan-Meier Estimate Medical prognosis Medical statistics Medical treatment missing value Models, Statistical Precision medicine Prognosis Randomized Controlled Trials as Topic - methods Regression Analysis Treatment Outcome precision medicine missing value differential treatment effect bootstrap
ISSN:	0277-6715, 1097-0258, 1097-0258
Online Access:	Get full text
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