A 90‐day preclinical toxicological evaluation in rats of a highly purified and concentrated mulberry leaf extract

Mulberry (genus Morus) leaves have long been used as a human food, especially in Asia, and animal feed. More recently, mulberry leaf extracts have been introduced as a convenient way to consume mulberry for non‐nutritional functional effects. Reducose® 5% is an Morus alba leaf extract that has been...

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Bibliographic Details
Published in:	Journal of applied toxicology Vol. 44; no. 10; pp. 1504 - 1517
Main Authors:	Murbach, Timothy S., Glávits, Róbert, Endres, John R., Hirka, Gábor, Pasics Szakonyiné, Ilona
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01.10.2024
Subjects:	1-Deoxynojirimycin - analogs & derivatives 1-Deoxynojirimycin - toxicity 1‐deoxynojirimycin 90‐day study Administration, Oral Animal feed Animals Body weight Body Weight - drug effects DNJ Dose-Response Relationship, Drug Feeds Female Global marketing Histopathology Leaves Male Morus - chemistry Morus alba mulberry leaf extract, MLE No-Observed-Adverse-Effect Level NOAEL OECD 408 Organ Size - drug effects Pathology Piperidine Plant extracts Plant Extracts - toxicity Plant Leaves - chemistry Rats Rats, Wistar Reducose Side effects Toxicity Toxicity testing Toxicity Tests, Subchronic Toxicology toxicity DNJ 90‐day study NOAEL mulberry leaf extract, MLE 1‐deoxynojirimycin Reducose Morus alba OECD 408
ISSN:	0260-437X, 1099-1263, 1099-1263
Online Access:	Get full text
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