Evaluation of the genotoxic potential of protoporphyrin IX and the safety of a protoporphyrin IX‐rich algal biomass

Chlamydomonas reinhardtii is a nonpathogenic, nontoxigenic green algae used as a sustainable source of protein in foods. In order to mimic meat‐like qualities, a strain rich in protoporphyrin IX (PPIX), an endogenous heme/chlorophyll precursor, was developed using an evolution and selection strategy...

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Vydané v:	Journal of applied toxicology Ročník 42; číslo 7; s. 1253 - 1275
Hlavní autori:	Murbach, Timothy S., Glávits, Róbert, Moghadam Maragheh, Niloofar, Endres, John R., Hirka, Gábor, Goodman, Richard E., Lu, Guihua, Vértesi, Adél, Béres, Erzsébet, Pasics Szakonyiné, Ilona
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Wiley Subscription Services, Inc 01.07.2022
Predmet:	Algae Animals Aquatic plants Biocompatibility Biomass Chlamydomonas reinhardtii Chlorophyll Chromosome aberrations Digestibility DNA Damage Genotoxicity Heme In vitro methods and tests In vivo methods and tests Mammals Mammals - metabolism Meat meat substitute Mutation NOAEL Organs Pepsin Protein sources Proteins Proteomics Protoporphyrin Protoporphyrin IX Protoporphyrins - metabolism Protoporphyrins - toxicity Rats Safety Target recognition Toxicity toxicity meat substitute protoporphyrin IX Chlamydomonas reinhardtii safety NOAEL
ISSN:	0260-437X, 1099-1263, 1099-1263
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