The role of Shh signalling pathway in central nervous system development and related diseases

Sonic hedgehog (Shh) plays important roles in developmental of vertebrate animal central nervous system (CNS), and Gli is its downstream signal molecule. Shh signalling is essential for pattern formation, cell‐fate specification, axon guidance, proliferation, survival and differentiation of neurons...

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Bibliographic Details
Published in:	Cell biochemistry and function Vol. 39; no. 2; pp. 180 - 189
Main Authors:	Li, Xiaoying, Li, Yunxiao, Li, Shuanqing, Li, Han, Yang, Ciqing, Lin, Juntang
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01.03.2021
Subjects:	Autism Axon guidance Brain Brain cancer Brain research Brain tumors Cell differentiation Central nervous system Differentiation (biology) Epilepsy Head injuries Hedgehog protein Movement disorders Nervous system Nervous system diseases Neurodegenerative diseases Parkinson's disease Pattern formation Signal classification Signal transduction Signaling signalling pathway Sonic hedgehog Spinal cord Traumatic brain injury Tumors Vertebrates Sonic hedgehog spinal cord signalling pathway brain central nervous system
ISSN:	0263-6484, 1099-0844, 1099-0844
Online Access:	Get full text
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