Purification and characterization of a novel antifungal protein with antiproliferation and anti-HIV-1 reverse transcriptase activities from Peganum harmala seeds

A novel antifungal protein, designated as PHP, was isolated from the seeds of Peganum harmala, by cationic exchange chromatography on Resource S column and gel filtration on Sephadex 75 10/300 GL column. PHP was found to form a homodimer of about 16 kDa. Isoelectric focusing polyacrylamide gel elect...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Acta biochimica et biophysica Sinica Jg. 45; H. 2; S. 87
Hauptverfasser:	Ma, Xiaojin, Liu, Dongliang, Tang, Haishu, Wang, Yan, Wu, Ting, Li, Yang, Yang, Jie, Yang, Jianhua, Sun, Surong, Zhang, Fuchun
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	China 01.02.2013
Schlagworte:	Antifungal Agents - chemistry Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Cell Line, Tumor Cell Proliferation - drug effects Enzyme Activation HIV Reverse Transcriptase - antagonists & inhibitors Humans Peganum - chemistry Plant Proteins - chemistry Plant Proteins - isolation & purification Plant Proteins - pharmacology Seeds - chemistry
ISSN:	1745-7270, 1745-7270
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!