A biomimetic injectable chitosan/alginate hydrogel biocopmosites encapsulating selenium- folic acid nanoparticles for regeneration of spinal cord injury: An in vitro study

Spinal cord injury (SCI) poses significant challenges to regenerative medicine due to its limited self-repair capabilities. In this study, we engineered a biomimetic injectable hydrogel using modified chitosan and alginate biopolymers encapsulating selenium-folic acid nanoparticles (Se-FA NPs) to fa...

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Bibliographic Details
Published in:	International journal of biological macromolecules Vol. 288; p. 138682
Main Authors:	Farzan, Mahan, Soleimannejad, Mostafa, Shariat, Saeedeh, Heidari Sureshjani, Mina, Gholipour, Abolfazl, Ashrafi Dehkordi, Korosh, Alerasoul Dehkordi, Seyed Mohammad Reza, Farzan, Mahour
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.02.2025
Subjects:	alginates Alginates - chemistry animal injuries Animals bioactive properties biocompatibility biocomposites Biomimetic Materials - chemistry Biomimetic Materials - pharmacology biomimetics biopolymers cell growth Cell Proliferation - drug effects Cell Survival - drug effects cell viability chitosan Chitosan - chemistry Electrospinning Folic acid Folic Acid - chemistry Folic Acid - pharmacology gene expression Humans Hydrogel hydrogels Hydrogels - chemistry Hydrogels - pharmacology medicine nanofibers nanoparticles Nanoparticles - chemistry Oxidized alginate Selenium - chemistry Selenium - pharmacology Selenium nanoparticles spinal cord Spinal Cord Injuries - drug therapy Spinal Cord Injuries - therapy Spinal cord injury Spinal Cord Regeneration - drug effects therapeutics tissue repair Oxidized alginate Electrospinning Hydrogel Spinal cord injury Selenium nanoparticles Folic acid
ISSN:	0141-8130, 1879-0003, 1879-0003
Online Access:	Get full text
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