HLA-DQ beta-chain restriction fragment length polymorphism as a risk marker in type 1 (insulin-dependent) diabetes mellitus: a Finnish family study

Finnish Type 1 (insulin-dependent) diabetic families were analysed for HLA-DQ beta-chain polymorphism using a short intron-specific probe. A simple hybridization pattern was obtained in which all fragments were associated significantly with Type 1 diabetes. The simultaneous presence of two different...

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Veröffentlicht in:	Diabetologia Jg. 33; H. 6; S. 357
Hauptverfasser:	Reijonen, H, Ilonen, J, Knip, M, Michelsen, B, Akerblom, H K
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Germany 01.06.1990
Schlagworte:	Adolescent Alleles B-Lymphocytes - immunology Biomarkers - analysis Child Deoxyribonuclease BamHI Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Finland Genotype Haplotypes HLA-DQ Antigens - genetics HLA-DQ beta-Chains HLA-DR Antigens - genetics Humans Polymorphism, Restriction Fragment Length Reference Values Risk Factors Finland
ISSN:	0012-186X
Online-Zugang:	Weitere Angaben
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