Isolation and characterization of a novel lectin with antifungal and antiproliferative activities from Sophora alopecuroides seeds

Sophora alopecuroides lectin (SAL), a novel lectin from the seeds of Sophora alopecuroides, was purified by ion-exchange chromatography on diethylaminoethyl (DEAE)- and carboxymethyl (CM)-Sepharose columns, followed by gel filtration on a Sephadex 75 10/300 GL column. SAL was found to be a monomer o...

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Bibliographic Details
Published in:	Acta biochimica et biophysica Sinica Vol. 44; no. 7; p. 606
Main Authors:	Li, Tingting, Yin, Xiaoli, Liu, Dongliang, Ma, Xiaojin, Lv, Hui, Sun, Surong
Format:	Journal Article
Language:	English
Published:	China 01.07.2012
Subjects:	Alternaria - drug effects Alternaria - growth & development Amino Acid Sequence Animals Cell Line, Tumor Cell Proliferation - drug effects Chromatography, High Pressure Liquid Dose-Response Relationship, Drug Electrophoresis, Polyacrylamide Gel Fungi - drug effects Fungi - growth & development Glycine - analogs & derivatives Glycine - chemistry HeLa Cells Hemagglutination Tests Humans Inhibitory Concentration 50 Mycelium - drug effects Mycelium - growth & development Penicillium - drug effects Penicillium - growth & development Plant Lectins - genetics Plant Lectins - isolation & purification Plant Lectins - pharmacology Rabbits Seeds - chemistry Sophora - chemistry
ISSN:	1745-7270, 1745-7270
Online Access:	Get more information
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