Use of Composite End Points in Early and Intermediate Age-Related Macular Degeneration Clinical Trials: State-of-the-Art and Future Directions

The slow progression of early age-related macular degeneration (AMD) stages to advanced AMD requires the use of surrogate end points in clinical trials. The use of combined end points may allow for shorter and smaller trials due to increased precision. We performed a literature search for the use of...

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Vydané v:	Ophthalmologica (Basel) Ročník 244; číslo 5; s. 387 - 395
Hlavní autori:	Terheyden, Jan Henrik, Schmitz-Valckenberg, Steffen, Crabb, David P., Dunbar, Hannah, Luhmann, Ulrich F.O., Behning, Charlotte, Schmid, Matthias, Silva, Rufino, Cunha-Vaz, José, Tufail, Adnan, Weissgerber, Georges, Leal, Sergio, Holz, Frank G., Finger, Robert P.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Basel, Switzerland 01.11.2021
Predmet:	Review Article Age-related macular degeneration Trial outcomes Composite end points
ISBN:	9783318070378, 3318070378
ISSN:	0030-3755, 1423-0267, 1423-0267
On-line prístup:	Získať plný text
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