Is an integrative laboratory algorithm more effective in detecting alpha-1-antitrypsin deficiency in patients with premature chronic obstructive pulmonary disease than AAT concentration based screening approach?

Alpha-1-antitrypsin deficiency (AATD), genetic risk factor for premature chronic obstructive pulmonary disease (COPD), often remains undetected. The aim of our study was to analyse the effectiveness of an integrative laboratory algorithm for AATD detection in patients diagnosed with COPD by the age...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemia medica Jg. 24; H. 2; S. 293 - 298
Hauptverfasser:	Beletic, Andjelo, Dudvarski-ilic, Aleksandra, Milenkovic, Branislava, Nagorni-Obradovic, Ljudmila, Ljujic, Mila, Djordjevic, Valentina, Mirkovic, Dusko, Radojkovic, Dragica, Majkic-Singh, Nada
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Croatia Croatian Society of Medical Biochemistry and Laboratory Medicine 01.01.2014
Schlagworte:	Adult Aged Algorithms Alleles alpha 1-Antitrypsin - blood alpha 1-Antitrypsin - genetics alpha 1-Antitrypsin Deficiency - blood alpha 1-Antitrypsin Deficiency - complications alpha 1-Antitrypsin Deficiency - diagnosis alpha 1-Antitrypsin Deficiency - genetics Cross-Sectional Studies Female Genetic Predisposition to Disease Genetic Testing - methods Heterozygote Humans Immunoassay Isoelectric Focusing Male Middle Aged Nephelometry and Turbidimetry Original Papers Polymerase Chain Reaction Pulmonary Disease, Chronic Obstructive - blood Pulmonary Disease, Chronic Obstructive - diagnosis Pulmonary Disease, Chronic Obstructive - etiology Pulmonary Disease, Chronic Obstructive - genetics Sequence Analysis, DNA
ISSN:	1846-7482, 1330-0962, 1846-7482
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!