Zieve Syndrome in a Patient With Hepatitis C

Zieve syndrome is a very rare syndrome that presents as a triad of hemolytic anemia, jaundice, and transient hyperlipidemia in patients with alcoholic liver disease. Herein, we present a case of a 30-year-old female with alcoholic liver disease and chronic hepatitis C. She presented with altered men...

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Veröffentlicht in:Curēus (Palo Alto, CA) Jg. 14; H. 5; S. e25412
Hauptverfasser: Haider, Asad A, Salabei, Joshua K, Hashmi, Mariam, Ismail, Zeeshan, Zheng, Mingyue, Iyer, Uma G
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Springer Nature B.V 27.05.2022
Cureus
Schlagworte:
Abdomen
Alcohol use
Anemia
Ascites
Blood products
Blood transfusions
Case reports
Cholesterol
Enzymes
Gastroenterology
Hematology
Hemoglobin
Hepatitis
Hepatitis C
High density lipoprotein
Hypotheses
Internal Medicine
Lipids
Lipoproteins
Liver diseases
Pancreatitis
Pathogenesis
Patients
Steroids
zieve syndrome
alcohol-related liver disease
alcohol use
zieve's disease
acute hemolytic anemia
chronic liver disease (cld)
s: anemia
hepatitis c (hcv) infection
ISSN:2168-8184, 2168-8184
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Abstract Zieve syndrome is a very rare syndrome that presents as a triad of hemolytic anemia, jaundice, and transient hyperlipidemia in patients with alcoholic liver disease. Herein, we present a case of a 30-year-old female with alcoholic liver disease and chronic hepatitis C. She presented with altered mental status and profound jaundice and was subsequently found to have acute hemolytic anemia due to Zieve syndrome. All other causes of hemolytic anemia were ruled out. She abstained from alcohol and received blood transfusions as needed, leading to the improvement of her anemia. This case highlights the need for more medical education about Zieve syndrome as the under-recognition of the disease can lead to unnecessary treatments. We review the existing literature to explain the epidemiology, pathogenesis, diagnosis, and treatment of Zieve syndrome. This case represents a rare presentation of Zieve syndrome in a patient with hepatitis C, and we have hypothesized a possible role of chronic hepatitis C infection in its pathophysiology.
AbstractList Zieve syndrome is a very rare syndrome that presents as a triad of hemolytic anemia, jaundice, and transient hyperlipidemia in patients with alcoholic liver disease. Herein, we present a case of a 30-year-old female with alcoholic liver disease and chronic hepatitis C. She presented with altered mental status and profound jaundice and was subsequently found to have acute hemolytic anemia due to Zieve syndrome. All other causes of hemolytic anemia were ruled out. She abstained from alcohol and received blood transfusions as needed, leading to the improvement of her anemia. This case highlights the need for more medical education about Zieve syndrome as the under-recognition of the disease can lead to unnecessary treatments. We review the existing literature to explain the epidemiology, pathogenesis, diagnosis, and treatment of Zieve syndrome. This case represents a rare presentation of Zieve syndrome in a patient with hepatitis C, and we have hypothesized a possible role of chronic hepatitis C infection in its pathophysiology.Zieve syndrome is a very rare syndrome that presents as a triad of hemolytic anemia, jaundice, and transient hyperlipidemia in patients with alcoholic liver disease. Herein, we present a case of a 30-year-old female with alcoholic liver disease and chronic hepatitis C. She presented with altered mental status and profound jaundice and was subsequently found to have acute hemolytic anemia due to Zieve syndrome. All other causes of hemolytic anemia were ruled out. She abstained from alcohol and received blood transfusions as needed, leading to the improvement of her anemia. This case highlights the need for more medical education about Zieve syndrome as the under-recognition of the disease can lead to unnecessary treatments. We review the existing literature to explain the epidemiology, pathogenesis, diagnosis, and treatment of Zieve syndrome. This case represents a rare presentation of Zieve syndrome in a patient with hepatitis C, and we have hypothesized a possible role of chronic hepatitis C infection in its pathophysiology.
Zieve syndrome is a very rare syndrome that presents as a triad of hemolytic anemia, jaundice, and transient hyperlipidemia in patients with alcoholic liver disease. Herein, we present a case of a 30-year-old female with alcoholic liver disease and chronic hepatitis C. She presented with altered mental status and profound jaundice and was subsequently found to have acute hemolytic anemia due to Zieve syndrome. All other causes of hemolytic anemia were ruled out. She abstained from alcohol and received blood transfusions as needed, leading to the improvement of her anemia. This case highlights the need for more medical education about Zieve syndrome as the under-recognition of the disease can lead to unnecessary treatments. We review the existing literature to explain the epidemiology, pathogenesis, diagnosis, and treatment of Zieve syndrome. This case represents a rare presentation of Zieve syndrome in a patient with hepatitis C, and we have hypothesized a possible role of chronic hepatitis C infection in its pathophysiology.
Author Hashmi, Mariam
Ismail, Zeeshan
Salabei, Joshua K
Iyer, Uma G
Haider, Asad A
Zheng, Mingyue
AuthorAffiliation 1 Internal Medicine, University of Central Florida College of Medicine, Graduate Medical Education/Hospital Corporation of America (HCA) Florida North Florida Hospital, Gainesville, USA
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Cites_doi 10.1080/08998280.2020.1735238
10.1097/00000441-196805000-00002
10.1038/ajg.2016.25
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10.7326/0003-4819-110-9-685
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Issue 5
Keywords zieve syndrome
alcohol-related liver disease
alcohol use
zieve's disease
acute hemolytic anemia
chronic liver disease (cld)
s: anemia
hepatitis c (hcv) infection
Language English
License Copyright © 2022, Haider et al.
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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StartPage e25412
SubjectTerms Abdomen
Alcohol use
Anemia
Ascites
Blood products
Blood transfusions
Case reports
Cholesterol
Enzymes
Gastroenterology
Hematology
Hemoglobin
Hepatitis
Hepatitis C
High density lipoprotein
Hypotheses
Internal Medicine
Lipids
Lipoproteins
Liver diseases
Pancreatitis
Pathogenesis
Patients
Steroids
Title Zieve Syndrome in a Patient With Hepatitis C
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