Dabigatran effects on the international normalized ratio, activated partial thromboplastin time, thrombin time, and fibrinogen: a multicenter, in vitro study

Patients receiving the direct thrombin inhibitor dabigatran may have selected anticoagulation assays performed as part of routine care. The effect of dabigatran on the international normalized ratio (INR), activated partial thromboplastin time (aPTT), thrombin time (TT), and fibrinogen requires clar...

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Bibliographic Details
Published in:	The Annals of pharmacotherapy Vol. 46; no. 12; p. 1627
Main Authors:	Dager, William E, Gosselin, Robert C, Kitchen, Steve, Dwyre, Dennis
Format:	Journal Article
Language:	English
Published:	United States 01.12.2012
Subjects:	Antithrombins - administration & dosage Antithrombins - pharmacology Benzimidazoles - administration & dosage Benzimidazoles - pharmacology Canada Dabigatran Dose-Response Relationship, Drug Fibrinogen - metabolism Humans In Vitro Techniques International Normalized Ratio Partial Thromboplastin Time Prodrugs Pyridines - administration & dosage Pyridines - pharmacology Reproducibility of Results Thrombin Time United Kingdom United States
ISSN:	1542-6270, 1542-6270
Online Access:	Get more information
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