GPCRchimeraDB: A Database of Chimeric G Protein-Coupled Receptors (GPCRs) to Assist Their Design

[Display omitted] •GPCRchimeraDB is a database that collects previously designed chimeric GPCRs.•A chimeric GPCR is obtained by merging 2 natural GPCRs.•Chimeric GPCRs enable to increase understanding in poorly characterized GPCRs.•GPCRchimeraDB describes and visualizes chimeric and natural GPCRs ex...

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Veröffentlicht in:	Journal of molecular biology Jg. 437; H. 14; S. 169164
Hauptverfasser:	Crauwels, Charlotte, Díaz, Adrián, Vranken, Wim
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier Ltd 15.07.2025
Schlagworte:	chimera class Databases, Protein G protein-coupled receptor GPCR Humans hybrid ligands molecular biology protein design Protein Engineering - methods Receptors, G-Protein-Coupled - chemistry Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Signal Transduction therapeutics G protein-coupled receptor chimera GPCR hybrid protein design
ISSN:	0022-2836, 1089-8638, 1089-8638
Online-Zugang:	Volltext
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