Saliva-based point-of-care assay to measure the concentration of pyrazinamide using a mobile UV spectrophotometer

Pyrazinamide, one of the first-line antituberculosis drugs, displays variability in drug exposure that is associated with treatment response. A simple, low-cost assay may be helpful to optimize treatment. This study aimed to develop and validate a point-of-care assay to quantify the concentration of...

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Bibliographic Details

Published in:	Journal of antimicrobial chemotherapy Vol. 80; no. 1; p. 254
Main Authors:	Chen, Ricky Hao, Nguyen, Thi Anh, Kim, Hannah Yejin, Stocker, Sophie L, Alffenaar, Jan-Willem C
Format:	Journal Article
Language:	English
Published:	England 03.01.2025
Subjects:	Adult Antitubercular Agents - analysis Drug Monitoring - methods Female Humans Male Point-of-Care Systems Pyrazinamide - analysis Reproducibility of Results Saliva - chemistry Sensitivity and Specificity Spectrophotometry, Ultraviolet - methods
ISSN:	1460-2091, 1460-2091
Online Access:	Get more information
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