The CD28-B7 Family in Anti-Tumor Immunity: Emerging Concepts in Cancer Immunotherapy

The interactions between B7 molecules and CD28-family receptors are crucial in the regulation of adaptive cellular immunity. In cancer, the aberrant expression of co-inhibitory B7 molecules has been attributed to reduced anti-tumor immunity and cancer immune evasion, prompting the development of can...

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Veröffentlicht in:	Immune network Jg. 14; H. 6; S. 265
Hauptverfasser:	Leung, Joanne, Suh, Woong-Kyung
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Korea (South) 01.12.2014
Schlagworte:	CD28 family B7 family Immune evasion Co-stimulation Cancer immunotherapy Co-inhibition
ISSN:	1598-2629
Online-Zugang:	Weitere Angaben
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