Zirconium-catalysed N-acylation of lactams using unactivated carboxylic acids

[Display omitted] •New method for the catalytic N-acylation of lactams with carboxylic acids.•Screening of Lewis acid catalysts for N-acylation of pyroglutamic acid methyl ester.•Yields up to 97% were reached with 10 mol% Zr(propoxide)4.•Substrate scope was investigated; with 57–97% yield achieved.•...

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Vydané v:	Tetrahedron letters Ročník 59; číslo 17; s. 1646 - 1650
Hlavní autori:	Hulsbosch, Joris, Claes, Laurens, De Vos, Dirk E.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	OXFORD Elsevier Ltd 25.04.2018 Elsevier
Predmet:	Aniracetam Catalysis catalysts chemical reactions Chemistry Chemistry, Organic drugs Lactam lactams Lewis acids moieties N-Acylation palmitic acid pesticides Physical Sciences Science & Technology surfactants temperature zirconium Zirconyl chloride Zirconyl chloride Catalysis Aniracetam Lactam N-Acylation CHEMISTRY DISORDERS CHLORIDE
ISSN:	0040-4039, 1873-3581
On-line prístup:	Získať plný text
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