Greater aortic stiffness is associated with lower hippocampal cerebrovascular reserve but not cerebral blood flow or amyloid in middle-aged and older adults

Background Recent studies suggests cerebrovascular dysfunction precedes amyloid deposition and cognitive impairment in Alzheimer’s disease (AD). However, if functional impairments in the hippocampus, as evidenced by reduced hippocampal cerebral blood flow (CBF) during memory stimulation and cerebrov...

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Bibliographic Details
Published in:Artery research Vol. 24; no. 1; p. 63
Main Authors: DuBose, Lyndsey E., Boles Ponto, Laura L., Moser, David J., Pierce, Gary L.
Format: Journal Article
Language:English
Published: Dordrecht Elsevier B.V 01.12.2018
Springer Netherlands
Springer Nature B.V
BMC
Subjects:
ISSN:1872-9312, 1876-4401, 1876-4401
Online Access:Get full text
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