Genotypic Resistance of Pyrazinamide but Not Minimum Inhibitory Concentration Is Associated With Longer Time to Sputum Culture Conversion in Patients With Multidrug-resistant Tuberculosis

Pyrazinamide (PZA) resistance in multidrug-resistant tuberculosis (MDR-TB) is common; yet, it is not clear how it affects interim and treatment outcomes. Although rarely performed, phenotypic drug susceptibility testing (pDST) is used to define PZA resistance, but genotypic DST (gDST) and minimum in...

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Veröffentlicht in:Clinical infectious diseases Jg. 73; H. 9; S. e3511
Hauptverfasser: Kuhlin, Johanna, Davies Forsman, Lina, Mansjö, Mikael, Jonsson Nordvall, Michaela, Wijkander, Maria, Wagrell, Charlotta, Jonsson, Jerker, Groenheit, Ramona, Werngren, Jim, Schön, Thomas, Bruchfeld, Judith
Format: Journal Article
Sprache:Englisch
Veröffentlicht: 02.11.2021
ISSN:1537-6591, 1537-6591
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