Peripheral neuropathy in non-Hodgkin's lymphoma patients receiving vincristine with and without aprepitant/fosaprepitant

Peripheral neuropathy is a common treatment-related adverse effect associated with vincristine. Vincristine is a major CYP3A4 substrate and is often administered alongside the neurokinin-1 (NK-1) receptor antagonists, aprepitant or fosaprepitant, which are moderate CYP3A4 inhibitors. This inhibition...

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Bibliographic Details

Published in:	Journal of oncology pharmacy practice Vol. 26; no. 4; p. 809
Main Authors:	Edwards, Jessi K, Bossaer, John B, Lewis, Paul O, Sant, Ashley
Format:	Journal Article
Language:	English
Published:	England 01.06.2020
Subjects:	Aprepitant neuropathy vincristine fosaprepitant drug interaction
ISSN:	1477-092X, 1477-092X
Online Access:	Get more information
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