Superwettable nanodendritic gold substrates for direct miRNA SERS detection

By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and th...

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Veröffentlicht in:Nanoscale Jg. 10; H. 45; S. 20990
Hauptverfasser: Song, Yongchao, Xu, Tailin, Xu, Li-Ping, Zhang, Xueji
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England 07.12.2018
Schlagworte:
Dendrimers - chemistry
DNA Probes - metabolism
Gold - chemistry
Hydrophobic and Hydrophilic Interactions
MicroRNAs - analysis
MicroRNAs - metabolism
Nanostructures - chemistry
Rhodamines - chemistry
Spectrum Analysis, Raman
Surface Properties
ISSN:2040-3372, 2040-3372
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Zusammenfassung:By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and the superwettable interface ensures the immobilization of droplets in superhydrophilic microwells, which hold great potentials for applications in disease diagnostics.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2040-3372
2040-3372
DOI:10.1039/c8nr07348a