Superwettable nanodendritic gold substrates for direct miRNA SERS detection

By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and th...

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Veröffentlicht in:Nanoscale Jg. 10; H. 45; S. 20990
Hauptverfasser: Song, Yongchao, Xu, Tailin, Xu, Li-Ping, Zhang, Xueji
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England 07.12.2018
Schlagworte:
Dendrimers - chemistry
DNA Probes - metabolism
Gold - chemistry
Hydrophobic and Hydrophilic Interactions
MicroRNAs - analysis
MicroRNAs - metabolism
Nanostructures - chemistry
Rhodamines - chemistry
Spectrum Analysis, Raman
Surface Properties
ISSN:2040-3372, 2040-3372
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Abstract By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and the superwettable interface ensures the immobilization of droplets in superhydrophilic microwells, which hold great potentials for applications in disease diagnostics.
AbstractList By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and the superwettable interface ensures the immobilization of droplets in superhydrophilic microwells, which hold great potentials for applications in disease diagnostics.By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and the superwettable interface ensures the immobilization of droplets in superhydrophilic microwells, which hold great potentials for applications in disease diagnostics.
By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and the superwettable interface ensures the immobilization of droplets in superhydrophilic microwells, which hold great potentials for applications in disease diagnostics.
Author Song, Yongchao
Zhang, Xueji
Xu, Li-Ping
Xu, Tailin
Author_xml – sequence: 1
  givenname: Yongchao
  surname: Song
  fullname: Song, Yongchao
  email: xutailin@ustb.edu.cn, xuliping@ustb.edu.cn, zhangxueji@ustb.edu.cn
  organization: Research Center for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China. xutailin@ustb.edu.cn xuliping@ustb.edu.cn zhangxueji@ustb.edu.cn
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  givenname: Tailin
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  fullname: Xu, Tailin
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  givenname: Li-Ping
  surname: Xu
  fullname: Xu, Li-Ping
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  givenname: Xueji
  surname: Zhang
  fullname: Zhang, Xueji
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30406246$$D View this record in MEDLINE/PubMed
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Snippet By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS...
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SubjectTerms Dendrimers - chemistry
DNA Probes - metabolism
Gold - chemistry
Hydrophobic and Hydrophilic Interactions
MicroRNAs - analysis
MicroRNAs - metabolism
Nanostructures - chemistry
Rhodamines - chemistry
Spectrum Analysis, Raman
Surface Properties
Title Superwettable nanodendritic gold substrates for direct miRNA SERS detection
URI https://www.ncbi.nlm.nih.gov/pubmed/30406246
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Volume 10
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