Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype

Molecular profiling in cancer has identified potential actionable drug targets that have prompted attempts to discover clinically validated biomarkers to guide therapeutic decision-making and enrollment to clinical trials. We evaluated whether comprehensive genetic analysis of patients with pancreat...

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Veröffentlicht in:	Clinical cancer research Jg. 23; H. 20; S. 6094
Hauptverfasser:	Lowery, Maeve A, Jordan, Emmet J, Basturk, Olca, Ptashkin, Ryan N, Zehir, Ahmet, Berger, Michael F, Leach, Tanisha, Herbst, Brian, Askan, Gokce, Maynard, Hannah, Glassman, Danielle, Covington, Christina, Schultz, Nikolaus, Abou-Alfa, Ghassan K, Harding, James J, Klimstra, David S, Hechtman, Jaclyn F, Hyman, David M, Allen, Peter J, Jarnagin, William R, Balachandran, Vinod P, Varghese, Anna M, Schattner, Mark A, Yu, Kenneth H, Saltz, Leonard B, Solit, David B, Iacobuzio-Donahue, Christine A, Leach, Steven D, O'Reilly, Eileen M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 15.10.2017
Schlagworte:	Carcinoma, Pancreatic Ductal - diagnosis Carcinoma, Pancreatic Ductal - genetics DNA Damage Female Gene Frequency Genetic Association Studies Genetic Testing Genetic Variation Genome-Wide Association Study Genomics High-Throughput Nucleotide Sequencing Humans Male Neoplasm Staging Oncogenes Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - genetics Phenotype
ISSN:	1078-0432, 1557-3265, 1557-3265
Online-Zugang:	Weitere Angaben
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