Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas

Gliomas are the most important group of malignant primary brain tumors and one of the most aggressive forms of cancer. During the last years, several studies have demonstrated that cannabinoids induce apoptosis of glioma cells and inhibit angiogenesis of gliomas in vivo. As the effects of cannabinoi...

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Vydáno v:	Neurochemistry international Ročník 56; číslo 6-7; s. 829 - 833
Hlavní autoři:	De Jesús, Maider López, Hostalot, Cristina, Garibi, Jesús M., Sallés, Joan, Meana, J. Javier, Callado, Luis F.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Kidlington Elsevier 01.05.2010
Témata:	Adult Aged Astrocytoma - chemistry Benzoxazines - pharmacology Biological and medical sciences Blotting, Western Brain Chemistry Brain Neoplasms - chemistry Cannabinoids - pharmacology Cell Membrane - chemistry Female Fundamental and applied biological sciences. Psychology Glioblastoma - chemistry Glioma - chemistry Guanosine 5'-O-(3-Thiotriphosphate) - metabolism Humans Male Medical sciences Meningioma - chemistry Middle Aged Morpholines - pharmacology Naphthalenes - pharmacology Neuropharmacology Pharmacology. Drug treatments Psychodysleptics: hallucinogen Psychology. Psychoanalysis. Psychiatry Psychopharmacology Receptor, Cannabinoid, CB1 - analysis Receptor, Cannabinoid, CB1 - drug effects Receptor, Cannabinoid, CB1 - metabolism Receptor, Cannabinoid, CB2 - analysis Receptor, Cannabinoid, CB2 - drug effects Receptor, Cannabinoid, CB2 - metabolism Sulfur Radioisotopes Vertebrates: nervous system and sense organs Human CB1 cannabinoid receptor Glial cell Cannabinoids Neuroglia Central nervous system Human brain Cannabinoid Encephalon Glial tumors
ISSN:	0197-0186, 1872-9754, 1872-9754
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