Reductions in positive Clostridioides difficile events reportable to National Healthcare Safety Network (NHSN) with adoption of reflex enzyme immunoassay (EIA) testing in 13 Atlanta hospitals

In total, 13 facilities changed C. difficile testing to reflexive testing by enzyme immunoassay (EIA) only after a positive nucleic acid-amplification test (NAAT); the standardized infection ratio (SIR) decreased by 46% (range, −12% to −71% per hospital). Changing testing practice greatly influenced...

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Bibliographic Details
Published in:Infection control and hospital epidemiology Vol. 43; no. 7; pp. 935 - 938
Main Authors: Goodenough, Dana, Sefton, Samantha, Overton, Elizabeth, Smith, Elizabeth, Kraft, Colleen S., Varkey, Jay B., Fridkin, Scott K.
Format: Journal Article
Language:English
Published: New York, USA Cambridge University Press 01.07.2022
Subjects:
Business metrics
Concise Communication
Enzymes
Immunoassay
Infections
Medical laboratories
Nucleic acids
Patient safety
Surveillance
Atlanta Georgia
United States > US
Georgia
ISSN:0899-823X, 1559-6834, 1559-6834
Online Access:Get full text
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Summary:In total, 13 facilities changed C. difficile testing to reflexive testing by enzyme immunoassay (EIA) only after a positive nucleic acid-amplification test (NAAT); the standardized infection ratio (SIR) decreased by 46% (range, −12% to −71% per hospital). Changing testing practice greatly influenced a performance metric without changing C. difficile infection prevention practice.
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ISSN:0899-823X
1559-6834
1559-6834
DOI:10.1017/ice.2021.145