Change surface regression for nonlinear subgroup identification with application to warfarin pharmacogenomics data

Pharmacogenomics stands as a pivotal driver toward personalized medicine, aiming to optimize drug efficacy while minimizing adverse effects by uncovering the impact of genetic variations on inter-individual outcome variability. Despite its promise, the intricate landscape of drug metabolism introduc...

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Vydané v:	Biometrics Ročník 81; číslo 1
Hlavní autori:	Liu, Pan, Li, Yaguang, Li, Jialiang
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 07.01.2025
Predmet:	Algorithms Anticoagulants - administration & dosage Computer Simulation Humans Models, Statistical Nonlinear Dynamics Pharmacogenetics - methods Pharmacogenetics - statistics & numerical data Precision Medicine Regression Analysis Warfarin - administration & dosage Warfarin - pharmacokinetics change surface pharmacogenomics warfarin dosing treatment recommendation personalized medicine subgroup identification
ISSN:	0006-341X, 1541-0420, 1541-0420
On-line prístup:	Získať plný text
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