Tryptophan-specific peptide modification through metal-free photoinduced N-H alkylation employing N-aryl glycines

Tryptophan (Trp) carries a unique heteroaromatic indole side chain and plays a critical role in peptide or protein modification. Herein, we have reported a metal-free photoinduced N-H alkylation strategy using N-aryl glycines for specific modification of tryptophan-containing peptides. The robustnes...

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Bibliographic Details

Published in:	Chinese chemical letters Vol. 35; no. 6; pp. 109244 - 319
Main Authors:	Yin, Jianhui, Huang, Wenjing, Guo, Changyong, Liu, Chao, Gao, Fei, Hu, Honggang
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01.06.2024 School of Medicine or Institute of Translation Medicine,Shanghai University,Shanghai 200444,China
Subjects:	Glycine Modification Peptide Photoinduced Tryptophan Tryptophan Modification Glycine Peptide Photoinduced
ISSN:	1001-8417, 1878-5964
Online Access:	Get full text
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