Developing new antidotes for poisons with existing effective treatments: a case study of fomepizole in paracetamol poisoning

Acetylcysteine is the only effective and licensed therapy for paracetamol poisoning. However, acetylcysteine loses efficacy if treatment is delayed 8-12 hours after paracetamol ingestion, and there is also uncertainty as to whether the dose should be increased in high-risk paracetamol ingestions. St...

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Bibliographic Details
Published in:Clinical toxicology (Philadelphia, Pa.) Vol. 61; no. 8; pp. 577 - 580
Main Authors: Dear, James W., Bateman, D. Nicholas
Format: Journal Article
Language:English
Published: 03.08.2023
ISSN:1556-3650, 1556-9519, 1556-9519
Online Access:Get full text
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