Developing new antidotes for poisons with existing effective treatments: a case study of fomepizole in paracetamol poisoning

Acetylcysteine is the only effective and licensed therapy for paracetamol poisoning. However, acetylcysteine loses efficacy if treatment is delayed 8-12 hours after paracetamol ingestion, and there is also uncertainty as to whether the dose should be increased in high-risk paracetamol ingestions. St...

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Veröffentlicht in:	Clinical toxicology (Philadelphia, Pa.) Jg. 61; H. 8; S. 577 - 580
Hauptverfasser:	Dear, James W., Bateman, D. Nicholas
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	03.08.2023
ISSN:	1556-3650, 1556-9519, 1556-9519
Online-Zugang:	Volltext
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