The Associations of Lens Power With Age and Axial Length in Healthy Chinese Children and Adolescents Aged 6 to 18 Years

To investigate the relationship between lens power and age as well as the relationship between lens power and axial length (AL) in Chinese children and adolescents. The participants underwent a comprehensive ophthalmic examination that included AL, cycloplegic refraction, and Pentacam measurements....

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Vydané v:Investigative ophthalmology & visual science Ročník 58; číslo 13; s. 5849
Hlavní autori: Xiong, Shuyu, Zhang, Bo, Hong, Yuan, He, Xiangui, Zhu, Jianfeng, Zou, Haidong, Xu, Xun
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 01.11.2017
Predmet:
Adolescent
Aging - physiology
Asian Continental Ancestry Group
Axial Length, Eye - physiology
Biometry
Child
China - epidemiology
Cross-Sectional Studies
Female
Healthy Volunteers
Humans
Lens, Crystalline - physiology
Male
Refraction, Ocular
ISSN:1552-5783, 1552-5783
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Shrnutí:To investigate the relationship between lens power and age as well as the relationship between lens power and axial length (AL) in Chinese children and adolescents. The participants underwent a comprehensive ophthalmic examination that included AL, cycloplegic refraction, and Pentacam measurements. The crystalline lens power was calculated using Bennett's formula and then compared among the children of different age groups, refractive statuses, and AL categories. The association of lens power and AL was analyzed using multiple regression. A total of 1992 children and adolescents aged 6- to 18-years old were included. The difference in lens power was greater before 10-years old, followed by a relatively smaller difference in children aged 10 to 14 years and the difference in lens power came to a near plateau in adolescents after 14-years old. The negative association between lens power and AL was found to be more evident in nonmyopes than in myopes irrespective of age (younger than 10 years: nonmyopes: β = -1.499, myopes: β = -0.872; older than 10 years: nonmyopes: β = -1.288, myopes: β = -0.390, all P < 0.001). The lens power in children and adolescents aged 6 to 18 years exhibited three stages. The association between lens power and AL differed between the nonmyopes and myopes. These findings suggested that less reduction in lens power might be associated with both growing age and increasing AL in myopes.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1552-5783
1552-5783
DOI:10.1167/iovs.17-22639