Oat avenanthramide-C (2c) is biotransformed by mice and the human microbiota into bioactive metabolites

Avenanthramides (AVAs), which are found exclusively in oats, may play an important role in anti-inflammation and antiatherogenesis. Although the bioavailability of AVAs has been investigated previously, little is known about their metabolism. The aim of the present study was to investigate the metab...

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Vydané v:	The Journal of nutrition Ročník 145; číslo 2; s. 239
Hlavní autori:	Wang, Pei, Chen, Huadong, Zhu, Yingdong, McBride, Jennifer, Fu, Junsheng, Sang, Shengmin
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.02.2015
Predmet:	Adult Animals Apoptosis - drug effects Avena - chemistry Biotransformation Body Mass Index Caffeic Acids - urine Chromatography, High Pressure Liquid Coumaric Acids - urine Feces - microbiology Female HCT116 Cells Healthy Volunteers Humans Male Mice Microbiota ortho-Aminobenzoates - administration & dosage ortho-Aminobenzoates - pharmacokinetics ortho-Aminobenzoates - urine Spectrometry, Mass, Electrospray Ionization 2c interindividual variation oat colon cancer cells avenanthramide-C apoptosis metabolism mice human microbiota
ISSN:	1541-6100, 1541-6100
On-line prístup:	Zistit podrobnosti o prístupe
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