Factor v Leiden mutation in severe infection and sepsis

In severe infection and sepsis, activation of coagulation frequently occurs, which contributes to the development of multiple organ dysfunction. Factor V Leiden is a relatively common mutation resulting in a mild prohemostatic state and consequently with an increased tendency to develop thrombosis....

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Bibliographic Details

Published in:	Seminars in thrombosis and hemostasis Vol. 37; no. 8; p. 955
Main Authors:	Levi, Marcel, Schouten, Marcel, van't Veer, Cees, van der Poll, Tom
Format:	Journal Article
Language:	English
Published:	United States 01.11.2011
Subjects:	Animals Factor V - genetics Humans Infection - blood Infection - genetics Mice Mutation Sepsis - blood Sepsis - genetics Thrombophilia - blood Thrombophilia - genetics Thrombophilia - microbiology
ISSN:	1098-9064, 1098-9064
Online Access:	Get more information
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