Phenylbutyrate-induced glutamine depletion in humans: effect on leucine metabolism

The present study was designed to determine whether sodium phenylbutyrate (ΦB) acutely induces a decrease in plasma glutamine in healthy humans, and, if so, will decrease estimates of whole body protein synthesis. In a first group of three healthy subjects, graded doses (0, 0.18, and 0.36 g ⋅ kg ⋅ d...

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Bibliographic Details

Published in:	American journal of physiology: endocrinology and metabolism Vol. 274; no. 5; p. E801
Main Authors:	Darmaun, Dominique, Welch, Susan, Rini, Annie, Sager, Brenda K, Altomare, Astride, Haymond, Morey W
Format:	Journal Article
Language:	English
Published:	United States 01.05.1998
Subjects:	stable isotopes nutrition protein metabolism radioactive tracers
ISSN:	0002-9513, 1522-1555
Online Access:	Get more information
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