Air Pollution, Genetic Factors, and the Risk of Lung Cancer: A Prospective Study in the UK Biobank

Both genetic and environmental factors contribute to lung cancer, but the degree to which air pollution modifies the impact of genetic susceptibility on lung cancer remains unknown. To investigate whether air pollution and genetic factors jointly contribute to incident lung cancer. We analyzed data...

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Veröffentlicht in:	American journal of respiratory and critical care medicine Jg. 204; H. 7; S. 817
Hauptverfasser:	Huang, Yanqian, Zhu, Meng, Ji, Mengmeng, Fan, Jingyi, Xie, Junxing, Wei, Xiaoxia, Jiang, Xiangxiang, Xu, Jing, Chen, Liang, Yin, Rong, Wang, Yuzhuo, Dai, Juncheng, Jin, Guangfu, Xu, Lin, Hu, Zhibin, Ma, Hongxia, Shen, Hongbing
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.10.2021
Schlagworte:	Adult Aged Air Pollutants - analysis Air Pollutants - toxicity Air Pollution - adverse effects Air Pollution - analysis Air Pollution - statistics & numerical data Biological Specimen Banks Environmental Exposure - adverse effects Environmental Exposure - analysis Environmental Exposure - statistics & numerical data Female Follow-Up Studies Gene-Environment Interaction Genetic Predisposition to Disease Humans Lung Neoplasms - epidemiology Lung Neoplasms - etiology Male Middle Aged Nitrogen Oxides - toxicity Particulate Matter - analysis Particulate Matter - toxicity Polymorphism, Single Nucleotide Proportional Hazards Models Prospective Studies Risk Factors United Kingdom - epidemiology United Kingdom lung cancer air pollution genetic susceptibility additive interaction
ISSN:	1535-4970, 1535-4970
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