α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model

Parkinson's disease is one of the most common movement disorders and is characterized by dopaminergic cell loss and the accumulation of pathological α-synuclein, but its precise pathogenetic mechanisms remain elusive. To develop disease-modifying therapies for Parkinson's disease, an anima...

Full description

Bibliographic Details

Published in:	Brain (London, England : 1878) Vol. 143; no. 1; p. 249
Main Authors:	Taguchi, Tomoyuki, Ikuno, Masashi, Hondo, Mari, Parajuli, Laxmi Kumar, Taguchi, Katsutoshi, Ueda, Jun, Sawamura, Masanori, Okuda, Shinya, Nakanishi, Etsuro, Hara, Junko, Uemura, Norihito, Hatanaka, Yusuke, Ayaki, Takashi, Matsuzawa, Shuichi, Tanaka, Masaki, El-Agnaf, Omar M A, Koike, Masato, Yanagisawa, Masashi, Uemura, Maiko T, Yamakado, Hodaka, Takahashi, Ryosuke
Format:	Journal Article
Language:	English
Published:	England 01.01.2020
Subjects:	alpha-synuclein RBD prodromal PD Parkinson’s disease hyposmia
ISSN:	1460-2156, 1460-2156
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!