Characterizing Distress and Identifying Modifiable Intervention Targets for Family Caregivers of Patients with Malignant Gliomas
Individuals caring for patients with malignant gliomas experience high rates of anxiety; however, an in-depth understanding of their distress and evidence-based interventions to target their needs are lacking. We conducted semistructured interviews with caregivers with elevated anxiety to characteri...
Uloženo v:
| Vydáno v: | Journal of palliative medicine Ročník 26; číslo 1; s. 17 |
|---|---|
| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
United States
01.01.2023
|
| Témata: | |
| ISSN: | 1557-7740, 1557-7740 |
| On-line přístup: | Zjistit podrobnosti o přístupu |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Individuals caring for patients with malignant gliomas experience high rates of anxiety; however, an in-depth understanding of their distress and evidence-based interventions to target their needs are lacking.
We conducted semistructured interviews with caregivers with elevated anxiety to characterize their drivers of anxiety, identify modifiable intervention targets, and capture their preferences for a psychosocial intervention.
From 9/2017 to 3/2019, we conducted semistructured interviews with 21 caregivers of patients with malignant gliomas, at time points following the patient's diagnosis or within one to three months after the patient's death.
Eligible caregivers in the United States had clinically significant anxiety as measured by a Hospital Anxiety and Depression Scale-Anxiety score >7.
Three independent coders employed thematic content analysis to analyze the qualitative data with NVivo 12, achieving high intercoder agreement (Kappa = 0.98).
On average, caregivers were 54.81 years old (
10.85) with elevated anxiety (
10.90,
3.25). We identified six themes in which caregivers described (1) coping through reassurance seeking or avoidance, (2) changes in their relationship with the patient, (3) challenges with social support, (4) vacillation between certainty and uncertainty regarding the future, (5) devaluation of self-care for the patients' needs, and (6) challenges communicating with the health care team. Caregivers were interested in an intervention soon after the patient's diagnosis, yet expressed concern about finding the time to participate.
Emergent themes characterized the distress experienced by caregivers of patients with malignant gliomas and provided insight into their psychosocial intervention preferences. We identified evidence-based intervention components based on the modifiable factors arising from these themes. |
|---|---|
| AbstractList | Individuals caring for patients with malignant gliomas experience high rates of anxiety; however, an in-depth understanding of their distress and evidence-based interventions to target their needs are lacking.
We conducted semistructured interviews with caregivers with elevated anxiety to characterize their drivers of anxiety, identify modifiable intervention targets, and capture their preferences for a psychosocial intervention.
From 9/2017 to 3/2019, we conducted semistructured interviews with 21 caregivers of patients with malignant gliomas, at time points following the patient's diagnosis or within one to three months after the patient's death.
Eligible caregivers in the United States had clinically significant anxiety as measured by a Hospital Anxiety and Depression Scale-Anxiety score >7.
Three independent coders employed thematic content analysis to analyze the qualitative data with NVivo 12, achieving high intercoder agreement (Kappa = 0.98).
On average, caregivers were 54.81 years old (
10.85) with elevated anxiety (
10.90,
3.25). We identified six themes in which caregivers described (1) coping through reassurance seeking or avoidance, (2) changes in their relationship with the patient, (3) challenges with social support, (4) vacillation between certainty and uncertainty regarding the future, (5) devaluation of self-care for the patients' needs, and (6) challenges communicating with the health care team. Caregivers were interested in an intervention soon after the patient's diagnosis, yet expressed concern about finding the time to participate.
Emergent themes characterized the distress experienced by caregivers of patients with malignant gliomas and provided insight into their psychosocial intervention preferences. We identified evidence-based intervention components based on the modifiable factors arising from these themes. Background: Individuals caring for patients with malignant gliomas experience high rates of anxiety; however, an in-depth understanding of their distress and evidence-based interventions to target their needs are lacking. Objective: We conducted semistructured interviews with caregivers with elevated anxiety to characterize their drivers of anxiety, identify modifiable intervention targets, and capture their preferences for a psychosocial intervention. Design: From 9/2017 to 3/2019, we conducted semistructured interviews with 21 caregivers of patients with malignant gliomas, at time points following the patient's diagnosis or within one to three months after the patient's death. Setting/Subjects: Eligible caregivers in the United States had clinically significant anxiety as measured by a Hospital Anxiety and Depression Scale-Anxiety score >7. Measurements: Three independent coders employed thematic content analysis to analyze the qualitative data with NVivo 12, achieving high intercoder agreement (Kappa = 0.98). Results: On average, caregivers were 54.81 years old (SD = 10.85) with elevated anxiety (M = 10.90, SD = 3.25). We identified six themes in which caregivers described (1) coping through reassurance seeking or avoidance, (2) changes in their relationship with the patient, (3) challenges with social support, (4) vacillation between certainty and uncertainty regarding the future, (5) devaluation of self-care for the patients' needs, and (6) challenges communicating with the health care team. Caregivers were interested in an intervention soon after the patient's diagnosis, yet expressed concern about finding the time to participate. Conclusions: Emergent themes characterized the distress experienced by caregivers of patients with malignant gliomas and provided insight into their psychosocial intervention preferences. We identified evidence-based intervention components based on the modifiable factors arising from these themes.Background: Individuals caring for patients with malignant gliomas experience high rates of anxiety; however, an in-depth understanding of their distress and evidence-based interventions to target their needs are lacking. Objective: We conducted semistructured interviews with caregivers with elevated anxiety to characterize their drivers of anxiety, identify modifiable intervention targets, and capture their preferences for a psychosocial intervention. Design: From 9/2017 to 3/2019, we conducted semistructured interviews with 21 caregivers of patients with malignant gliomas, at time points following the patient's diagnosis or within one to three months after the patient's death. Setting/Subjects: Eligible caregivers in the United States had clinically significant anxiety as measured by a Hospital Anxiety and Depression Scale-Anxiety score >7. Measurements: Three independent coders employed thematic content analysis to analyze the qualitative data with NVivo 12, achieving high intercoder agreement (Kappa = 0.98). Results: On average, caregivers were 54.81 years old (SD = 10.85) with elevated anxiety (M = 10.90, SD = 3.25). We identified six themes in which caregivers described (1) coping through reassurance seeking or avoidance, (2) changes in their relationship with the patient, (3) challenges with social support, (4) vacillation between certainty and uncertainty regarding the future, (5) devaluation of self-care for the patients' needs, and (6) challenges communicating with the health care team. Caregivers were interested in an intervention soon after the patient's diagnosis, yet expressed concern about finding the time to participate. Conclusions: Emergent themes characterized the distress experienced by caregivers of patients with malignant gliomas and provided insight into their psychosocial intervention preferences. We identified evidence-based intervention components based on the modifiable factors arising from these themes. |
| Author | Mesa, Michelle Temel, Jennifer S Forst, Deborah A Jacobs, Jamie M Kaslow-Zieve, Emilia R Sereno, Isabella Quain, Kit M Greer, Joseph A Hansen, Andrea Landay, Sophia L El-Jawahri, Areej |
| Author_xml | – sequence: 1 givenname: Deborah A orcidid: 0000-0002-8428-0841 surname: Forst fullname: Forst, Deborah A organization: Harvard Medical School, Boston, Massachusetts, USA – sequence: 2 givenname: Emilia R surname: Kaslow-Zieve fullname: Kaslow-Zieve, Emilia R organization: Massachusetts General Hospital, Boston, Massachusetts, USA – sequence: 3 givenname: Andrea surname: Hansen fullname: Hansen, Andrea organization: Massachusetts General Hospital, Boston, Massachusetts, USA – sequence: 4 givenname: Michelle surname: Mesa fullname: Mesa, Michelle organization: Massachusetts General Hospital, Boston, Massachusetts, USA – sequence: 5 givenname: Sophia L surname: Landay fullname: Landay, Sophia L organization: Massachusetts General Hospital, Boston, Massachusetts, USA – sequence: 6 givenname: Kit M surname: Quain fullname: Quain, Kit M organization: Massachusetts General Hospital, Boston, Massachusetts, USA – sequence: 7 givenname: Isabella surname: Sereno fullname: Sereno, Isabella organization: Massachusetts General Hospital, Boston, Massachusetts, USA – sequence: 8 givenname: Areej surname: El-Jawahri fullname: El-Jawahri, Areej organization: Harvard Medical School, Boston, Massachusetts, USA – sequence: 9 givenname: Joseph A surname: Greer fullname: Greer, Joseph A organization: Harvard Medical School, Boston, Massachusetts, USA – sequence: 10 givenname: Jennifer S surname: Temel fullname: Temel, Jennifer S organization: Harvard Medical School, Boston, Massachusetts, USA – sequence: 11 givenname: Jamie M surname: Jacobs fullname: Jacobs, Jamie M organization: Harvard Medical School, Boston, Massachusetts, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35708587$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNkE1PAjEYhBuDkQ89ejU9ellsu3S7Hg0qkkj0gGfybvsWSna72BYNnvzpQsTE00wyz8xh-qTjW4-EXHI25Ky8vVlvmqFggg-ZzEcnpMelVJlSI9b557ukH-OasX2ByTPSzaVipSxVj3yPVxBAJwzuy_klvXcxBYyRgjd0atAnZ3eHYNYaZx1UNdKp3-Mfh6j1dA5hiSlS2wb6CI2rd3QMAZfuA0OkraWvkNyejfTTpRWdQe2WHnyik9q1DcRzcmqhjnhx1AF5e3yYj5-y55fJdHz3nOlclClTVnPNS4kApTa5rbCShZbWjArO4LY0iNJUoHKppWalENxayatcycJYIbkYkOvf3U1o37cY06JxUWNdg8d2GxeiUEqqPC_EHr06otuqQbPYBNdA2C3-XhM__vhzwA |
| CitedBy_id | crossref_primary_10_1007_s00520_025_09890_z crossref_primary_10_1002_pon_70231 crossref_primary_10_1007_s00520_024_08783_x crossref_primary_10_1136_bmjopen_2022_069410 crossref_primary_10_1111_cns_70516 crossref_primary_10_1080_13803395_2025_2542245 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1089/jpm.2021.0534 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine Economics |
| EISSN | 1557-7740 |
| ExternalDocumentID | 35708587 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- .GJ 0R~ 0VX 34G 36B 39C 4.4 53G 5GY AAWTL ABBKN ABIVO ABJNI ACGFS ADBBV AENEX ALMA_UNASSIGNED_HOLDINGS BNQNF CAG CGR COF CS3 CUY CVF DU5 EBS ECM EIF EJD EMOBN F5P IM4 J5H LSO MV1 NPM NQHIM O9- P2P RML RMSOB UE5 7X8 AABVL AAETQ SCNPE |
| ID | FETCH-LOGICAL-c328t-7fc1c185eaa8cd3fbeb56c5fd4610a98dee5dba735c5c08221ff51b3756df2512 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 10 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000812286200001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1557-7740 |
| IngestDate | Thu Oct 02 06:29:33 EDT 2025 Thu Apr 03 07:03:44 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | anxiety brain tumor cognitive–behavioral therapy family caregivers cancer malignant glioma |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c328t-7fc1c185eaa8cd3fbeb56c5fd4610a98dee5dba735c5c08221ff51b3756df2512 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0002-8428-0841 |
| PMID | 35708587 |
| PQID | 2677573362 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_2677573362 pubmed_primary_35708587 |
| PublicationCentury | 2000 |
| PublicationDate | 2023-01-00 20230101 |
| PublicationDateYYYYMMDD | 2023-01-01 |
| PublicationDate_xml | – month: 01 year: 2023 text: 2023-01-00 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Journal of palliative medicine |
| PublicationTitleAlternate | J Palliat Med |
| PublicationYear | 2023 |
| SSID | ssj0008905 |
| Score | 2.4024217 |
| Snippet | Individuals caring for patients with malignant gliomas experience high rates of anxiety; however, an in-depth understanding of their distress and... Background: Individuals caring for patients with malignant gliomas experience high rates of anxiety; however, an in-depth understanding of their distress and... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 17 |
| SubjectTerms | Adaptation, Psychological Anxiety Caregivers - psychology Glioma Humans Middle Aged Patients |
| Title | Characterizing Distress and Identifying Modifiable Intervention Targets for Family Caregivers of Patients with Malignant Gliomas |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/35708587 https://www.proquest.com/docview/2677573362 |
| Volume | 26 |
| WOSCitedRecordID | wos000812286200001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1JS8NAFB7UinpxqVvdGMFrrMlklpxE1KqHlB4q9BYms5SIJNVUD5786c6SWi-C4CWHwECYvJn38d73fQ-AM6IRYZyQIFY8CuJIqIAjFAYSKUqRYMicKTdsgvb7bDRKBk3BrW5olbM70V3UshK2Rt6NCKXOuy-6nLwEdmqU7a42IzQWQQsZKGOjmo7mbuEscRRGkzKpQZHxReOxad53nyZWhh6F5yYI49_RpcsyvY3_ft8mWG_wJbzyAbEFFlTZBqsz-XHdBitp003fBp_X327NHyaDwZvCK0cgLyX0Cl6ngoJpJQtdWJEVfPjBkYRDRyOvoQG-0E_QgFbPNHZcD1hpOPCurTW05V6YGsw_tsQbePdcWF7SDnjs3Q6v74NmIkMgUMSmAdUiFCbDK86ZkEjnKsdEYC2taztPmFQKy5xThAUW1ks-1BqHOaKYSG2R1C5YKqtS7QNIsMGakchjluA4T3RiXYUSHgpiVnGtO-B0ts-ZiXjbxuClqt7qbL7THbDnf1Y28dYcGcLUYEhGD_6w-hCs2dnxvp5yBFranHd1DJbF-7SoX09cKJlnf5B-AeRS1kM |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Characterizing+Distress+and+Identifying+Modifiable+Intervention+Targets+for+Family+Caregivers+of+Patients+with+Malignant+Gliomas&rft.jtitle=Journal+of+palliative+medicine&rft.au=Forst%2C+Deborah+A&rft.au=Kaslow-Zieve%2C+Emilia+R&rft.au=Hansen%2C+Andrea&rft.au=Mesa%2C+Michelle&rft.date=2023-01-01&rft.eissn=1557-7740&rft.volume=26&rft.issue=1&rft.spage=17&rft_id=info:doi/10.1089%2Fjpm.2021.0534&rft_id=info%3Apmid%2F35708587&rft_id=info%3Apmid%2F35708587&rft.externalDocID=35708587 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1557-7740&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1557-7740&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1557-7740&client=summon |