Reversible intramyelinic cytotoxic edema in a patient with traumatic brain injury

We report a case demonstrating magnetic resonance imaging findings of reversible white matter restriction on diffusion-weighted imaging and apparent diffusion coefficient maps in a patient with traumatic brain injury. A 22-year-old man presented to the emergency department following a severe motor v...

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Veröffentlicht in:Neurological sciences Jg. 46; H. 10; S. 5427 - 5430
Hauptverfasser: Barragán, Catalina, González-Gómez, Silvia, Barrera, Adriana, Soler, Camilo
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Cham Springer International Publishing 01.10.2025
Springer Nature B.V
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ISSN:1590-1874, 1590-3478, 1590-3478
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Abstract We report a case demonstrating magnetic resonance imaging findings of reversible white matter restriction on diffusion-weighted imaging and apparent diffusion coefficient maps in a patient with traumatic brain injury. A 22-year-old man presented to the emergency department following a severe motor vehicle collision. The magnetic resonance imaging revealed multiple focal hemorrhagic contusions, supratentorial diffuse axonal injury, a left parietotemporal subdural laminar hematoma, and extensive diffusion restriction on diffusion coefficient maps involving the deep white matter of the centrum semiovale bilaterally, as well as the splenium of the corpus callosum. The patient was hospitalized, and follow-up magnetic resonance showed a complete resolution of the diffusion-restricted areas. This case illustrates a traumatic brain injury associated with transient, reversible intramyelinic cytotoxic edema.
AbstractList We report a case demonstrating magnetic resonance imaging findings of reversible white matter restriction on diffusion-weighted imaging and apparent diffusion coefficient maps in a patient with traumatic brain injury. A 22-year-old man presented to the emergency department following a severe motor vehicle collision. The magnetic resonance imaging revealed multiple focal hemorrhagic contusions, supratentorial diffuse axonal injury, a left parietotemporal subdural laminar hematoma, and extensive diffusion restriction on diffusion coefficient maps involving the deep white matter of the centrum semiovale bilaterally, as well as the splenium of the corpus callosum. The patient was hospitalized, and follow-up magnetic resonance showed a complete resolution of the diffusion-restricted areas. This case illustrates a traumatic brain injury associated with transient, reversible intramyelinic cytotoxic edema.
We report a case demonstrating magnetic resonance imaging findings of reversible white matter restriction on diffusion-weighted imaging and apparent diffusion coefficient maps in a patient with traumatic brain injury. A 22-year-old man presented to the emergency department following a severe motor vehicle collision. The magnetic resonance imaging revealed multiple focal hemorrhagic contusions, supratentorial diffuse axonal injury, a left parietotemporal subdural laminar hematoma, and extensive diffusion restriction on diffusion coefficient maps involving the deep white matter of the centrum semiovale bilaterally, as well as the splenium of the corpus callosum. The patient was hospitalized, and follow-up magnetic resonance showed a complete resolution of the diffusion-restricted areas. This case illustrates a traumatic brain injury associated with transient, reversible intramyelinic cytotoxic edema.We report a case demonstrating magnetic resonance imaging findings of reversible white matter restriction on diffusion-weighted imaging and apparent diffusion coefficient maps in a patient with traumatic brain injury. A 22-year-old man presented to the emergency department following a severe motor vehicle collision. The magnetic resonance imaging revealed multiple focal hemorrhagic contusions, supratentorial diffuse axonal injury, a left parietotemporal subdural laminar hematoma, and extensive diffusion restriction on diffusion coefficient maps involving the deep white matter of the centrum semiovale bilaterally, as well as the splenium of the corpus callosum. The patient was hospitalized, and follow-up magnetic resonance showed a complete resolution of the diffusion-restricted areas. This case illustrates a traumatic brain injury associated with transient, reversible intramyelinic cytotoxic edema.
Author Soler, Camilo
Barragán, Catalina
Barrera, Adriana
González-Gómez, Silvia
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  surname: Barragán
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  surname: González-Gómez
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  fullname: Barrera, Adriana
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  givenname: Camilo
  surname: Soler
  fullname: Soler, Camilo
  organization: Fundación Santa Fe de Bogotá
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Cites_doi 10.1177/1971400915598071
10.1080/02699050902841912
10.1148/rg.2017160085
10.1097/00001199-200307000-00003
10.1016/j.bbi.2012.06.008
10.3171/foc.2007.22.5.3
10.1097/00001199-200609000-00001
10.1594/ecr2013/C-2139
10.1016/S0303-8467(00)00079-2
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Keywords Cytotoxic edema
Traumatic brain injury
Centrum semiovale
Reversible intramyelinic cytotoxic edema
Corpus callosum
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SubjectTerms Brain Edema - diagnostic imaging
Brain Edema - etiology
Brain Edema - pathology
Brain Injuries, Traumatic - complications
Brain Injuries, Traumatic - diagnostic imaging
Brain Injuries, Traumatic - pathology
Brief Communication
Case reports
Corpus callosum
Cytokines
Cytotoxicity
Diffusion coefficient
Diffusion Magnetic Resonance Imaging
Edema
Emergency medical care
Glasgow Coma Scale
Head injuries
Hematoma
Humans
Ischemia
Magnetic Resonance Imaging
Male
Medicine
Medicine & Public Health
Nervous system
Neuroimaging
Neurology
Neuroradiology
Neurosurgery
Potassium
Psychiatry
Substantia alba
Trauma
Traumatic brain injury
Young Adult
Title Reversible intramyelinic cytotoxic edema in a patient with traumatic brain injury
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