IDH1 mutated prostate cancer with psammomatous calcifications: A case report and review of the literature
We report a case of grade group 2, pT 3 N0 Mx prostate acinar adenocarcinoma with intratumoural psammomatous calcifications and IDH1 mutation. This is an emerging molecular subtype of prostate cancer associated with a propensity for higher grade and stage of disease. The index case was of intermedia...
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| Vydané v: | Human Pathology Reports Ročník 42; s. 300800 |
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| Hlavní autori: | , , , , |
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01.11.2025
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| Abstract | We report a case of grade group 2, pT 3 N0 Mx prostate acinar adenocarcinoma with intratumoural psammomatous calcifications and IDH1 mutation. This is an emerging molecular subtype of prostate cancer associated with a propensity for higher grade and stage of disease. The index case was of intermediate grade but had locally advanced stage III disease. |
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| AbstractList | AbstractWe report a case of grade group 2, pT 3 N0 Mx prostate acinar adenocarcinoma with intratumoural psammomatous calcifications and IDH1 mutation. This is an emerging molecular subtype of prostate cancer associated with a propensity for higher grade and stage of disease. The index case was of intermediate grade but had locally advanced stage III disease. We report a case of grade group 2, pT 3 N0 Mx prostate acinar adenocarcinoma with intratumoural psammomatous calcifications and IDH1 mutation. This is an emerging molecular subtype of prostate cancer associated with a propensity for higher grade and stage of disease. The index case was of intermediate grade but had locally advanced stage III disease. |
| ArticleNumber | 300800 |
| Author | Gaskin, P.S. Gaskin, D.A. Reid, A. Depeiza, N. Nebhnani, J. |
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| Cites_doi | 10.1111/iju.15299 10.1007/s00345-018-2225-7 10.1016/j.eururo.2018.08.026 10.1038/nature19062 10.1016/j.modpat.2023.100146 10.3390/cells10092345 10.1016/j.modpat.2024.100616 10.1002/pros.22871 10.1038/nrurol.2015.298 10.1158/1538-7445.AM2020-3731 10.1002/1878-0261.13441 |
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| Keywords | IDH1 mutation Case report Psammomatous carcinoma Prostatic carcinoma Prostate cancer Afro-Caribbean |
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Oncol. doi: 10.1002/1878-0261.13441 |
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| Snippet | We report a case of grade group 2, pT 3 N0 Mx prostate acinar adenocarcinoma with intratumoural psammomatous calcifications and IDH1 mutation. This is an... AbstractWe report a case of grade group 2, pT 3 N0 Mx prostate acinar adenocarcinoma with intratumoural psammomatous calcifications and IDH1 mutation. This is... |
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| SubjectTerms | Afro-Caribbean Case report IDH1 mutation Pathology Prostate cancer Prostatic carcinoma Psammomatous carcinoma |
| Title | IDH1 mutated prostate cancer with psammomatous calcifications: A case report and review of the literature |
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