Chronic sternal osteomyelitis complicating primary manubriosternal septic arthritis

We present a 40-year-old woman complaining of worsening chest pain. She was previously treated with a prolonged course of antibiotics for suspected sternal osteomyelitis. Radiological investigations were suggestive of ongoing inflammation within the manubriosternal joint. Formal surgical debridement...

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Vydáno v:Clinical rheumatology Ročník 25; číslo 6; s. 934 - 936
Hlavní autoři: Sinha, S., Sinha, A., Nagarajah, K., Oei, E. L., Critchley, P., McNally, M. A.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Germany Springer Nature B.V 01.11.2006
Témata:
Adult
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - therapeutic use
Antibiotics
Arthritis, Infectious - complications
Arthritis, Infectious - diagnostic imaging
Arthritis, Infectious - drug therapy
Ceftriaxone - administration & dosage
Ceftriaxone - therapeutic use
Chronic Disease
Debridement
Female
Humans
Injections, Intravenous
Manubrium
Osteomyelitis - diagnostic imaging
Osteomyelitis - drug therapy
Osteomyelitis - etiology
Osteomyelitis - surgery
Radiography
Sternum
ISSN:0770-3198, 1434-9949
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Shrnutí:We present a 40-year-old woman complaining of worsening chest pain. She was previously treated with a prolonged course of antibiotics for suspected sternal osteomyelitis. Radiological investigations were suggestive of ongoing inflammation within the manubriosternal joint. Formal surgical debridement yielded evidence corroborating the diagnosis although microbiological samples were negative. Prolonged empirical treatment with intravenous antibiotics leads to a complete resolution of symptoms. Primary culture-negative manubriosternal septic arthritis is rare, and suboptimal treatment, particularly if confused with other conditions such as synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome, compounds its considerable morbidity.
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ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-005-0101-5