The Effect of a Patient Navigator on Treatment Abandonment and Follow-up for High Grade Osteosarcoma Patients in the Philippine General Hospital
Treatment abandonment for osteosarcoma is a significant problem in developing countries with rates as high as 70%. This study aimed to determine the effect of a patient navigator on treatment abandonment and patient follow-up of osteosarcoma patients at a tertiary referral center. A retrospective re...
Saved in:
| Published in: | Asian Pacific journal of cancer prevention : APJCP Vol. 22; no. 9; pp. 2873 - 2877 |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Thailand
West Asia Organization for Cancer Prevention
01.09.2021
|
| Subjects: | |
| ISSN: | 2476-762X, 1513-7368, 2476-762X |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Treatment abandonment for osteosarcoma is a significant problem in developing countries with rates as high as 70%. This study aimed to determine the effect of a patient navigator on treatment abandonment and patient follow-up of osteosarcoma patients at a tertiary referral center.
A retrospective review of osteosarcoma patients was performed investigating 2 cohorts based on the start of the patient navigator. Group 1 (Pre-Patient Navigator, n=46) were treated from January 2016 to December 2017 while Group 2 (Post-Patient Navigator, n=29) were treated from January 2018 to June 2019. The primary outcome investigated was treatment abandonment defined as missing 4 or more consecutive weeks of treatment. Semi-structured interviews were conducted to investigate the effect of the patient navigator on the cohorts.
Treatment abandonment rates for the Pre-Patient Navigator group was significantly higher compared to those with a patient navigator (50% vs 6%, p=0.0001). Abandonment for the pre-navigator group occurred at a mean of 2.9 months (0 - 9 months, median 3 months). Fourteen of 23 patients who abandoned from Group 1 did not proceed to neoadjuvant chemotherapy while 3 patients abandoned after completing 1 cycle of neoadjuvant chemotherapy. In the patient navigator group, no patients abandoned prior to completing 3 cycles of chemotherapy. One patient abandoned after refusing a below knee amputation after 3 cycles of neoadjuvant chemotherapy and 1 patient did not complete further chemotherapy after having a hip disarticulation. Patient feedback on the patient navigator experience was favorable.
Having a patient navigator from diagnosis throughout treatment reduced treatment abandonment rates in osteosarcoma patients and may serve as a model for other low to middle income countries. |
|---|---|
| AbstractList | Treatment abandonment for osteosarcoma is a significant problem in developing countries with rates as high as 70%. This study aimed to determine the effect of a patient navigator on treatment abandonment and patient follow-up of osteosarcoma patients at a tertiary referral center.
A retrospective review of osteosarcoma patients was performed investigating 2 cohorts based on the start of the patient navigator. Group 1 (Pre-Patient Navigator, n=46) were treated from January 2016 to December 2017 while Group 2 (Post-Patient Navigator, n=29) were treated from January 2018 to June 2019. The primary outcome investigated was treatment abandonment defined as missing 4 or more consecutive weeks of treatment. Semi-structured interviews were conducted to investigate the effect of the patient navigator on the cohorts.
Treatment abandonment rates for the Pre-Patient Navigator group was significantly higher compared to those with a patient navigator (50% vs 6%, p=0.0001). Abandonment for the pre-navigator group occurred at a mean of 2.9 months (0 - 9 months, median 3 months). Fourteen of 23 patients who abandoned from Group 1 did not proceed to neoadjuvant chemotherapy while 3 patients abandoned after completing 1 cycle of neoadjuvant chemotherapy. In the patient navigator group, no patients abandoned prior to completing 3 cycles of chemotherapy. One patient abandoned after refusing a below knee amputation after 3 cycles of neoadjuvant chemotherapy and 1 patient did not complete further chemotherapy after having a hip disarticulation. Patient feedback on the patient navigator experience was favorable.
Having a patient navigator from diagnosis throughout treatment reduced treatment abandonment rates in osteosarcoma patients and may serve as a model for other low to middle income countries. Treatment abandonment for osteosarcoma is a significant problem in developing countries with rates as high as 70%. This study aimed to determine the effect of a patient navigator on treatment abandonment and patient follow-up of osteosarcoma patients at a tertiary referral center.INTRODUCTIONTreatment abandonment for osteosarcoma is a significant problem in developing countries with rates as high as 70%. This study aimed to determine the effect of a patient navigator on treatment abandonment and patient follow-up of osteosarcoma patients at a tertiary referral center.A retrospective review of osteosarcoma patients was performed investigating 2 cohorts based on the start of the patient navigator. Group 1 (Pre-Patient Navigator, n=46) were treated from January 2016 to December 2017 while Group 2 (Post-Patient Navigator, n=29) were treated from January 2018 to June 2019. The primary outcome investigated was treatment abandonment defined as missing 4 or more consecutive weeks of treatment. Semi-structured interviews were conducted to investigate the effect of the patient navigator on the cohorts.MATERIALS AND METHODSA retrospective review of osteosarcoma patients was performed investigating 2 cohorts based on the start of the patient navigator. Group 1 (Pre-Patient Navigator, n=46) were treated from January 2016 to December 2017 while Group 2 (Post-Patient Navigator, n=29) were treated from January 2018 to June 2019. The primary outcome investigated was treatment abandonment defined as missing 4 or more consecutive weeks of treatment. Semi-structured interviews were conducted to investigate the effect of the patient navigator on the cohorts.Treatment abandonment rates for the Pre-Patient Navigator group was significantly higher compared to those with a patient navigator (50% vs 6%, p=0.0001). Abandonment for the pre-navigator group occurred at a mean of 2.9 months (0 - 9 months, median 3 months). Fourteen of 23 patients who abandoned from Group 1 did not proceed to neoadjuvant chemotherapy while 3 patients abandoned after completing 1 cycle of neoadjuvant chemotherapy. In the patient navigator group, no patients abandoned prior to completing 3 cycles of chemotherapy. One patient abandoned after refusing a below knee amputation after 3 cycles of neoadjuvant chemotherapy and 1 patient did not complete further chemotherapy after having a hip disarticulation. Patient feedback on the patient navigator experience was favorable.RESULTSTreatment abandonment rates for the Pre-Patient Navigator group was significantly higher compared to those with a patient navigator (50% vs 6%, p=0.0001). Abandonment for the pre-navigator group occurred at a mean of 2.9 months (0 - 9 months, median 3 months). Fourteen of 23 patients who abandoned from Group 1 did not proceed to neoadjuvant chemotherapy while 3 patients abandoned after completing 1 cycle of neoadjuvant chemotherapy. In the patient navigator group, no patients abandoned prior to completing 3 cycles of chemotherapy. One patient abandoned after refusing a below knee amputation after 3 cycles of neoadjuvant chemotherapy and 1 patient did not complete further chemotherapy after having a hip disarticulation. Patient feedback on the patient navigator experience was favorable.Having a patient navigator from diagnosis throughout treatment reduced treatment abandonment rates in osteosarcoma patients and may serve as a model for other low to middle income countries.CONCLUSIONSHaving a patient navigator from diagnosis throughout treatment reduced treatment abandonment rates in osteosarcoma patients and may serve as a model for other low to middle income countries. |
| Author | Alcasabas, Ana Patricia Estanislao, Jochrys Wang, Edward Gaston, Czar Louie Dimayuga, Cesar Fajardo, Pamela Quintos, Albert Taleon, Kathleen Rubio, Donnel Barsales, Ken |
| AuthorAffiliation | 2 Department of Pediatrics, College of Medicine and Philippine General Hospital, University of the Philippines Manila 1 Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila |
| AuthorAffiliation_xml | – name: 1 Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – name: 2 Department of Pediatrics, College of Medicine and Philippine General Hospital, University of the Philippines Manila |
| Author_xml | – sequence: 1 givenname: Czar Louie surname: Gaston fullname: Gaston, Czar Louie organization: Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 2 givenname: Kathleen surname: Taleon fullname: Taleon, Kathleen organization: Department of Pediatrics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 3 givenname: Ken surname: Barsales fullname: Barsales, Ken organization: Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 4 givenname: Cesar surname: Dimayuga fullname: Dimayuga, Cesar organization: Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 5 givenname: Jochrys surname: Estanislao fullname: Estanislao, Jochrys organization: Department of Pediatrics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 6 givenname: Pamela surname: Fajardo fullname: Fajardo, Pamela organization: Department of Pediatrics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 7 givenname: Albert surname: Quintos fullname: Quintos, Albert organization: Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 8 givenname: Donnel surname: Rubio fullname: Rubio, Donnel organization: Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 9 givenname: Edward surname: Wang fullname: Wang, Edward organization: Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila – sequence: 10 givenname: Ana Patricia surname: Alcasabas fullname: Alcasabas, Ana Patricia organization: Department of Pediatrics, College of Medicine and Philippine General Hospital, University of the Philippines Manila |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34582656$$D View this record in MEDLINE/PubMed |
| BookMark | eNpVUU1P3DAQtSqq8lF-QpGPXJImdmI7F6TVatkFobKHReIWjT-y6yqxQ-wF8S_4ybiUInqap5mn997MHKMD551B6EdZ5LSsa_5ztr6er3NSkDInJG9yIjj9go5IxVnGGbk_-IQP0XEIv4uiqgWvv6FDmgBhNTtCL5udwYuuMypi32HAa4jWuIh_waPdQvQT9g5vJgNx-NOeSXDauzecEL70fe-fsv2Iu0Rd2e0OLyfQBt-GaHyASfnhQzRg63BMhuud7e04Wmfw0jgzQY9XPow2Qv8dfe2gD-b0vZ6gu8vFZr7Kbm6XV_PZTaYoYTQTTItSg2KiIbRhstQSBIFKFlzyRhkuBW0qrZmuCKWVlLSivFNd2pqUlWL0BF381R33cjBapXgpRjtOdoDpufVg2_8nzu7arX9shaiLdOokcP4uMPmHvQmxHWxQpu_BGb8PLak557RklCfq2WevD5N_b6Cv9eGPuw |
| CitedBy_id | crossref_primary_10_1007_s40520_024_02926_0 crossref_primary_10_1016_j_healthplace_2025_103482 crossref_primary_10_1016_j_urology_2025_06_055 crossref_primary_10_1007_s11912_024_01514_9 crossref_primary_10_1002_pbc_30752 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 5PM |
| DOI | 10.31557/APJCP.2021.22.9.2873 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 2476-762X |
| EndPage | 2877 |
| ExternalDocumentID | PMC8850873 34582656 |
| Genre | Journal Article |
| GeographicLocations | Philippines |
| GeographicLocations_xml | – name: Philippines |
| GroupedDBID | CGR CUY CVF ECM EIF NPM 7X8 --- 23N 2WC 53G 5GY 5PM ADBBV ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BCNDV E3Z EBS EJD F5P FRJ GROUPED_DOAJ GX1 HYE JDI OK1 OVT RPM TR2 W2D WOW |
| ID | FETCH-LOGICAL-c3263-86d81dac6892396b1dba82a4b07b79ce7b8394dd6d42334bb3437fcf265214c63 |
| ISSN | 2476-762X 1513-7368 |
| IngestDate | Tue Nov 04 01:58:24 EST 2025 Fri Jul 11 04:28:49 EDT 2025 Thu Jan 02 22:54:57 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 9 |
| Keywords | LMIC (Low to middle income country) navigator abandonment osteosarcoma |
| Language | English |
| License | This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c3263-86d81dac6892396b1dba82a4b07b79ce7b8394dd6d42334bb3437fcf265214c63 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | http://dx.doi.org/10.31557/APJCP.2021.22.9.2873 |
| PMID | 34582656 |
| PQID | 2577731637 |
| PQPubID | 23479 |
| PageCount | 5 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_8850873 proquest_miscellaneous_2577731637 pubmed_primary_34582656 |
| PublicationCentury | 2000 |
| PublicationDate | 2021-Sep-01 20210901 |
| PublicationDateYYYYMMDD | 2021-09-01 |
| PublicationDate_xml | – month: 09 year: 2021 text: 2021-Sep-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | Thailand |
| PublicationPlace_xml | – name: Thailand – name: Iran |
| PublicationTitle | Asian Pacific journal of cancer prevention : APJCP |
| PublicationTitleAlternate | Asian Pac J Cancer Prev |
| PublicationYear | 2021 |
| Publisher | West Asia Organization for Cancer Prevention |
| Publisher_xml | – name: West Asia Organization for Cancer Prevention |
| SSID | ssj0045875 |
| Score | 2.332926 |
| Snippet | Treatment abandonment for osteosarcoma is a significant problem in developing countries with rates as high as 70%. This study aimed to determine the effect of... |
| SourceID | pubmedcentral proquest pubmed |
| SourceType | Open Access Repository Aggregation Database Index Database |
| StartPage | 2873 |
| SubjectTerms | Adolescent Female Hospitals, General Humans Male Neoplasm Grading Osteosarcoma - pathology Osteosarcoma - therapy Patient Dropouts - statistics & numerical data Patient Navigation - statistics & numerical data Philippines Retrospective Studies Tertiary Care Centers |
| Title | The Effect of a Patient Navigator on Treatment Abandonment and Follow-up for High Grade Osteosarcoma Patients in the Philippine General Hospital |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/34582656 https://www.proquest.com/docview/2577731637 https://pubmed.ncbi.nlm.nih.gov/PMC8850873 |
| Volume | 22 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 2476-762X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0045875 issn: 2476-762X databaseCode: DOA dateStart: 20000101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lj9MwELa2C1rtZcWbLrAyErcqpXXS2D5WgV0E25JDkXqr7DxEJZpUybYs_Ap-MuNH3HTVAyBxsVKncaeeL_bMeB4IvRklLAjEIPVoxnIvSAT3JM-lR4nM1PKYp4nOrn9Np1M2n_P4qOM1sTDbb7Qo2O0tX_9XVkMfMFuFzv4Fu92g0AHXwHRoge3Q_jHjbU5iHfsYm8ypsI5uVTqNslLnAzPnXz6WQhX0cL7mlwCM8ru3WWsHROUG0ruqRJr1PgMeyhomq1y5QevGTdLYZdZKZLWJrF1Fkrb4O9Yhm9YRsJ21IlHgq1TGgsb_Ulss44-Riz-7ErV19Y9-iqp3XW6WDpQz2ObMvcY7xJkZQLwVtq73p133u-VK_NgYo3KU1aJqWz_I0Ll32TUWts6eon0vdFVPUGQIjx3h7VV-6HvUN_V8-pnuIwENPdgZ5u2tgZDWK8Db6zwzBViszAAf6aH9yAdpTR2J6-nqK_r7hPR5v3m8Bcf1SuPRV-eY4ehOdnAtb8STiDGQp6nfQfcIHXHeWBCM4AFP6rzS7t-ZgDVNw9tDFJyik-bnDulXd92EW3LX7AE6swoTHhugP0RHWfEInUysS8hj9Avwjg3ecZljgS00scM7Lgvs8I5beMdwhR3eMbATK7xjjXfcxnszaI2XBQa84x3escU7bvD-BH25fD-LPni2zIiXgO7ieyxMQWkTSchA2eGhHKZSMCICOaCS8iSjEpSIQFVeA9XDD6T0A5_mSQ7zRoZBEvpP0XFRFtlzhHlKczpgXIZiBHjKGMkJTxlNk5SkRPIuet1M8wKWcXU2J4qs3NQL2DmpKiLn0y56ZqZ9sTb5ZhYNk7qI7jHEfUGliN-_Uyy_6lTxFjDn__zkC3S6e-1eouObapO9QveT7c2yri5Qh87ZhUYhtNN48hshVeiN |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+Effect+of+a+Patient+Navigator+on+Treatment+Abandonment+and+Follow-up+for+High+Grade+Osteosarcoma+Patients+in+the+Philippine+General+Hospital&rft.jtitle=Asian+Pacific+journal+of+cancer+prevention+%3A+APJCP&rft.au=Gaston%2C+Czar+Louie&rft.au=Taleon%2C+Kathleen&rft.au=Bersales%2C+Ken&rft.au=Dimayuga%2C+Cesar&rft.date=2021-09-01&rft.pub=West+Asia+Organization+for+Cancer+Prevention&rft.issn=1513-7368&rft.eissn=2476-762X&rft.volume=22&rft.issue=9&rft.spage=2873&rft.epage=2877&rft_id=info:doi/10.31557%2FAPJCP.2021.22.9.2873&rft_id=info%3Apmid%2F34582656&rft.externalDocID=PMC8850873 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2476-762X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2476-762X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2476-762X&client=summon |