Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnorma...

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Vydáno v:BJOG : an international journal of obstetrics and gynaecology Ročník 108; číslo 11; s. 1190 - 1192
Hlavní autoři: Kenyon, Anna P., Piercy, C. Nelson, Girling, J., Williamson, C., Tribe, R.M., Shennan, A.H.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Oxford, UK Blackwell Science Ltd 01.11.2001
Blackwell
Témata:
Adult
Biological and medical sciences
Cholestasis - complications
Cholestasis - physiopathology
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Humans
Liver Function Tests
Longitudinal Studies
Medical sciences
Pregnancy
Pregnancy Complications - physiopathology
Pregnancy. Fetus. Placenta
Prospective Studies
Pruritus - etiology
Human
Skin disease
Pregnancy disorders
Pruritus
Biliary tract disease
Case study
Pregnancy
Liver function
Cholostasis
Digestive diseases
Female
Skin
Diagnosis
Inaugural sign
ISSN:1470-0328, 1471-0528
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Popis
Shrnutí:Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1470-0328
1471-0528
DOI:10.1111/j.1471-0528.2003.00281.x