Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnorma...

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Veröffentlicht in:BJOG : an international journal of obstetrics and gynaecology Jg. 108; H. 11; S. 1190 - 1192
Hauptverfasser: Kenyon, Anna P., Piercy, C. Nelson, Girling, J., Williamson, C., Tribe, R.M., Shennan, A.H.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Oxford, UK Blackwell Science Ltd 01.11.2001
Blackwell
Schlagworte:
Adult
Biological and medical sciences
Cholestasis - complications
Cholestasis - physiopathology
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Humans
Liver Function Tests
Longitudinal Studies
Medical sciences
Pregnancy
Pregnancy Complications - physiopathology
Pregnancy. Fetus. Placenta
Prospective Studies
Pruritus - etiology
Human
Skin disease
Pregnancy disorders
Pruritus
Biliary tract disease
Case study
Pregnancy
Liver function
Cholostasis
Digestive diseases
Female
Skin
Diagnosis
Inaugural sign
ISSN:1470-0328, 1471-0528
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Abstract Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.
AbstractList Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.
Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.
Author Tribe, R.M.
Shennan, A.H.
Piercy, C. Nelson
Kenyon, Anna P.
Girling, J.
Williamson, C.
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  surname: Shennan
  fullname: Shennan, A.H.
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Cites_doi 10.1016/S0002-9378(94)70304-3
10.1016/S0146-0005(98)80042-6
10.1002/hep.510290450
10.1016/S0889-8553(21)00609-9
10.1080/13557859998173
10.1001/archderm.1994.01690060064006
10.1111/j.1471-0528.1997.tb11054.x
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Issue 11
Keywords Human
Skin disease
Pregnancy disorders
Pruritus
Biliary tract disease
Case study
Pregnancy
Liver function
Cholostasis
Digestive diseases
Female
Skin
Diagnosis
Inaugural sign
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Snippet Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the...
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SubjectTerms Adult
Biological and medical sciences
Cholestasis - complications
Cholestasis - physiopathology
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Humans
Liver Function Tests
Longitudinal Studies
Medical sciences
Pregnancy
Pregnancy Complications - physiopathology
Pregnancy. Fetus. Placenta
Prospective Studies
Pruritus - etiology
Title Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis
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