Fatal hepatotoxicity secondary to nimesulide

This report describes a 57-year-old female patient with chronic lumbago, who died from the sequelae of acute liver failure induced by nimesulide medication. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which preferentially inhibits cyclo-oxygenase 2 and has been associated with a tot...

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Veröffentlicht in:	European journal of clinical pharmacology Jg. 57; H. 4; S. 321 - 326
Hauptverfasser:	Merlani, Giorgio, Fox, Mark, Oehen, Hans-Peter, Cathomas, Gieri, Renner, Eberhard L., Fattinger, Karin, Schneemann, Markus, Kullak-Ublick, Gerd A.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Heidelberg Springer 01.07.2001 Berlin Springer Nature B.V
Schlagworte:	Biological and medical sciences Drug toxicity and drugs side effects treatment Liver Medical sciences Pharmacology. Drug treatments Side effects Toxicity: digestive system Human Prostaglandin-endoperoxide synthase Enzyme Isozyme Toxicity Liver Enzyme inhibitor Hepatic disease Non steroidal antiinflammatory agent Case study Digestive diseases Death Oxidoreductases Nimesulide
ISSN:	0031-6970, 1432-1041
Online-Zugang:	Volltext
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