A numerical method for osmotic water flow and solute diffusion with deformable membrane boundaries in two spatial dimension

Osmotic forces and solute diffusion are increasingly seen as playing a fundamental role in cell movement. Here, we present a numerical method that allows for studying the interplay between diffusive, osmotic and mechanical effects. An osmotically active solute obeys a advection–diffusion equation in...

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Vydáno v:Journal of computational physics Ročník 350; s. 728 - 746
Hlavní autoři: Yao, Lingxing, Mori, Yoichiro
Médium: Journal Article
Jazyk:angličtina
Vydáno: Cambridge Elsevier Inc 01.12.2017
Elsevier Science Ltd
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ISSN:0021-9991, 1090-2716
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Shrnutí:Osmotic forces and solute diffusion are increasingly seen as playing a fundamental role in cell movement. Here, we present a numerical method that allows for studying the interplay between diffusive, osmotic and mechanical effects. An osmotically active solute obeys a advection–diffusion equation in a region demarcated by a deformable membrane. The interfacial membrane allows transmembrane water flow which is determined by osmotic and mechanical pressure differences across the membrane. The numerical method is based on an immersed boundary method for fluid–structure interaction and a Cartesian grid embedded boundary method for the solute. We demonstrate our numerical algorithm with the test case of an osmotic engine, a recently proposed mechanism for cell propulsion.
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content type line 14
ISSN:0021-9991
1090-2716
DOI:10.1016/j.jcp.2017.09.006