CD44 Is Protective during Hyperoxia-Induced Lung Injury

Patients with acute lung injury or respiratory distress syndrome often require supplemental oxygen to maintain tissue oxygenation; however, this treatment can cause or worsen lung inflammation. CD44 is a transmembrane adhesion molecule that is present on a wide variety of cell types, including leuko...

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Bibliographic Details
Published in:	American journal of respiratory cell and molecular biology Vol. 44; no. 3; pp. 377 - 383
Main Authors:	Windt, Gerritje J. W. van der, Schouten, Marcel, Zeerleder, Sacha, Florquin, Sandrine, Poll, Tom van der
Format:	Journal Article
Language:	English
Published:	United States American Thoracic Society 01.03.2011
Subjects:	Animals Bronchoalveolar Lavage Fluid Hyaluronan Receptors - genetics Hyaluronan Receptors - physiology Hyaluronic Acid - chemistry Hyperoxia Inflammation Interleukin-6 - metabolism Leukocytes - cytology Lung - metabolism Lung Injury - metabolism Male Mice Mice, Inbred C57BL Mice, Knockout Neutrophils - cytology Neutrophils - metabolism
ISSN:	1044-1549, 1535-4989, 1535-4989
Online Access:	Get full text
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