The influence of ustekinumab on expression of STAT1, STAT3, STAT4, SOCS2, and IL17 in patients with psoriasis and in a control

The aim of this study was to assess changes in the expression of STAT1, STAT3, STAT4, SOCS2, and IL17 in psoriatic patients under ustekinumab treatment and in healthy volunteers. The study group consisted of 14 patients suffering from psoriasis vulgaris qualified for ustekinumab therapy (4 women, 10...

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Bibliographic Details
Published in:	Dermatologic therapy Vol. 32; no. 5; pp. e13029 - n/a
Main Authors:	Grabarek, Beniamin, Krzaczyński, Jakub, Strzałka‐Mrozik, Barbara, Wcisło‐Dziadecka, Dominika, Gola, Joanna
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01.09.2019
Subjects:	Adult Dermatologic Agents - pharmacology Female Gene Expression Regulation - drug effects Humans Interleukin-17 - biosynthesis Interleukin-17 - genetics JAK/STAT signaling pathway Male Middle Aged psoriasis Psoriasis - drug therapy Psoriasis - genetics Psoriasis - metabolism RNA - genetics Signal Transduction STAT1 Transcription Factor - biosynthesis STAT1 Transcription Factor - genetics STAT3 Transcription Factor - genetics STAT4 Transcription Factor - biosynthesis STAT4 Transcription Factor - genetics Suppressor of Cytokine Signaling Proteins - biosynthesis Suppressor of Cytokine Signaling Proteins - genetics ustekinumab Ustekinumab - pharmacology Young Adult psoriasis JAK/STAT signaling pathway ustekinumab
ISSN:	1396-0296, 1529-8019, 1529-8019
Online Access:	Get full text
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