Use of computer tomography imaging for analyzing bone remodeling around a percutaneous osseointegrated implant
Osseointegration (OI) is being used for the direct skeletal attachment of prosthetic limbs using an intramedullary stem that extends percutaneously from the subject's residual limb. For this technology to be successful, bone ingrowth and remodeling around the implant must occur. Physicians need...
Gespeichert in:
| Veröffentlicht in: | Journal of orthopaedic research Jg. 40; H. 9; S. 2065 - 2075 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
United States
01.09.2022
|
| Schlagworte: | |
| ISSN: | 0736-0266, 1554-527X, 1554-527X |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Osseointegration (OI) is being used for the direct skeletal attachment of prosthetic limbs using an intramedullary stem that extends percutaneously from the subject's residual limb. For this technology to be successful, bone ingrowth and remodeling around the implant must occur. Physicians need an effective way to assess bone remodeling to make informed treatment and rehabilitation decisions. Previous studies utilizing two‐dimensional imaging X‐ray as a tool to monitor bone‐remodeling around OI devices have limitations. This study describes methodology that was developed utilizing computed tomography (CT) imaging as a tool for analyzing bone remodeling around a percutaneous OI implant. Six transfemoral amputees implanted with a percutaneous osseointegrated prosthesis (POP) had CT scans taken of their residual femur at 6 and 52 weeks postoperatively. Three‐dimensional femoral models were processed using custom MATLAB script to collect cortical and medullary morphology measurements. Morphology data from 6‐ and 52‐week scans were compared to quantify bone remodeling around the POP implant. Fifty‐two weeks after implantation of the POP device, increases in cortical bone area and thickness were observed around the porous‐coated stem. Minimal changes were observed in the medullary canal parameters within the periprosthetic regions. This study successfully utilized CT imaging and three‐dimensional modeling techniques to analyze longitudinal data of bone remodeling around a transfemoral percutaneous implant. These methods have the potential to be used as a clinical tool for evaluating orthopedic implants in vivo. Data collected suggests that the POP device achieved the desired bone remodeling around the porous‐coated region of the implanted stem. |
|---|---|
| AbstractList | Osseointegration (OI) is being used for the direct skeletal attachment of prosthetic limbs using an intramedullary stem that extends percutaneously from the subject's residual limb. For this technology to be successful, bone ingrowth and remodeling around the implant must occur. Physicians need an effective way to assess bone remodeling to make informed treatment and rehabilitation decisions. Previous studies utilizing two‐dimensional imaging X‐ray as a tool to monitor bone‐remodeling around OI devices have limitations. This study describes methodology that was developed utilizing computed tomography (CT) imaging as a tool for analyzing bone remodeling around a percutaneous OI implant. Six transfemoral amputees implanted with a percutaneous osseointegrated prosthesis (POP) had CT scans taken of their residual femur at 6 and 52 weeks postoperatively. Three‐dimensional femoral models were processed using custom MATLAB script to collect cortical and medullary morphology measurements. Morphology data from 6‐ and 52‐week scans were compared to quantify bone remodeling around the POP implant. Fifty‐two weeks after implantation of the POP device, increases in cortical bone area and thickness were observed around the porous‐coated stem. Minimal changes were observed in the medullary canal parameters within the periprosthetic regions. This study successfully utilized CT imaging and three‐dimensional modeling techniques to analyze longitudinal data of bone remodeling around a transfemoral percutaneous implant. These methods have the potential to be used as a clinical tool for evaluating orthopedic implants in vivo. Data collected suggests that the POP device achieved the desired bone remodeling around the porous‐coated region of the implanted stem. Osseointegration (OI) is being used for the direct skeletal attachment of prosthetic limbs using an intramedullary stem that extends percutaneously from the subject's residual limb. For this technology to be successful, bone ingrowth and remodeling around the implant must occur. Physicians need an effective way to assess bone remodeling to make informed treatment and rehabilitation decisions. Previous studies utilizing two-dimensional imaging X-ray as a tool to monitor bone-remodeling around OI devices have limitations. This study describes methodology that was developed utilizing computed tomography (CT) imaging as a tool for analyzing bone remodeling around a percutaneous OI implant. Six transfemoral amputees implanted with a percutaneous osseointegrated prosthesis (POP) had CT scans taken of their residual femur at 6 and 52 weeks postoperatively. Three-dimensional femoral models were processed using custom MATLAB script to collect cortical and medullary morphology measurements. Morphology data from 6- and 52-week scans were compared to quantify bone remodeling around the POP implant. Fifty-two weeks after implantation of the POP device, increases in cortical bone area and thickness were observed around the porous-coated stem. Minimal changes were observed in the medullary canal parameters within the periprosthetic regions. This study successfully utilized CT imaging and three-dimensional modeling techniques to analyze longitudinal data of bone remodeling around a transfemoral percutaneous implant. These methods have the potential to be used as a clinical tool for evaluating orthopedic implants in vivo. Data collected suggests that the POP device achieved the desired bone remodeling around the porous-coated region of the implanted stem.Osseointegration (OI) is being used for the direct skeletal attachment of prosthetic limbs using an intramedullary stem that extends percutaneously from the subject's residual limb. For this technology to be successful, bone ingrowth and remodeling around the implant must occur. Physicians need an effective way to assess bone remodeling to make informed treatment and rehabilitation decisions. Previous studies utilizing two-dimensional imaging X-ray as a tool to monitor bone-remodeling around OI devices have limitations. This study describes methodology that was developed utilizing computed tomography (CT) imaging as a tool for analyzing bone remodeling around a percutaneous OI implant. Six transfemoral amputees implanted with a percutaneous osseointegrated prosthesis (POP) had CT scans taken of their residual femur at 6 and 52 weeks postoperatively. Three-dimensional femoral models were processed using custom MATLAB script to collect cortical and medullary morphology measurements. Morphology data from 6- and 52-week scans were compared to quantify bone remodeling around the POP implant. Fifty-two weeks after implantation of the POP device, increases in cortical bone area and thickness were observed around the porous-coated stem. Minimal changes were observed in the medullary canal parameters within the periprosthetic regions. This study successfully utilized CT imaging and three-dimensional modeling techniques to analyze longitudinal data of bone remodeling around a transfemoral percutaneous implant. These methods have the potential to be used as a clinical tool for evaluating orthopedic implants in vivo. Data collected suggests that the POP device achieved the desired bone remodeling around the porous-coated region of the implanted stem. |
| Author | Kubiak, Erik Sinclair, Sarina Agarwal, Jayant Drew, Alex Wankier, Zakary Taylor, Carolyn |
| Author_xml | – sequence: 1 givenname: Zakary orcidid: 0000-0003-0855-4182 surname: Wankier fullname: Wankier, Zakary organization: University of Utah – sequence: 2 givenname: Carolyn surname: Taylor fullname: Taylor, Carolyn organization: University of Utah – sequence: 3 givenname: Alex orcidid: 0000-0001-7743-4323 surname: Drew fullname: Drew, Alex organization: University of Utah – sequence: 4 givenname: Erik surname: Kubiak fullname: Kubiak, Erik organization: George E. Wahlen Department of Veterans Affairs Medical Center – sequence: 5 givenname: Jayant surname: Agarwal fullname: Agarwal, Jayant organization: Division of Plastic Surgery – sequence: 6 givenname: Sarina orcidid: 0000-0002-6334-9803 surname: Sinclair fullname: Sinclair, Sarina email: Sarina.Sinclair@hsc.utah.edu organization: George E. Wahlen Department of Veterans Affairs Medical Center |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34910325$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kUtrGzEUhUVxaWy3i_6BomW6mETSaEbjZTB5lUCgJJCduNZcuRNmpKmkITi_vnLsbEq7Ehd959zHWZCZ8w4J-crZGWdMnD_7cCYqIdUHMudVJYtKqKcZmTNV1gUTdX1CFjE-M8YUF80nclLKFWelqObEPUak3lLjh3FKGGjyg98GGH_taDfAtnNban2g4KDfve6rTe5NAw6-xX5fQ_CTaynQEYOZEjj0U6Q-RvSdS5i9ErbZa-zBpc_ko4U-4pfjuySPV5cP65vi7v76dn1xV5g8lSq45E0rYGUtl1atmqZh-YNLVW2ktKIFhXIFYColGiM3ta1RcVODaVmpEKFcktOD7xj87wlj0kMXDfb9YTwtas4ka6SsMvrtiE6bAVs9hrx32On3G2Xg_ACYkLcKaLXpEqTOuxSg6zVnep-CzinotxSy4vtfinfTf7FH95eux93_Qf3j_udB8QezbJjL |
| CitedBy_id | crossref_primary_10_1016_j_apmr_2022_06_008 |
| Cites_doi | 10.1016/j.injury.2011.03.031 10.1016/j.gaitpost.2020.05.018 10.1016/j.jmbbm.2012.06.015 10.1016/j.joca.2011.08.003 10.1016/j.clinbiomech.2020.01.017 10.1016/j.cmpb.2019.105102 10.1080/03093640701553922 10.1002/ar.22533 10.1002/jor.24421 10.3389/fendo.2015.00122 10.2106/JBJS.RVW.17.00037 10.1503/cjs.000511 10.1080/17453670710014806 10.1371/journal.pone.0221850 10.1098/rsta.1979.0048 10.1016/j.apmr.2016.02.024 10.1097/BRS.0b013e318240f981 10.1002/jor.23376 10.1016/S0883-5403(99)90063-3 10.1016/j.knee.2006.11.001 10.1002/jbmr.5650040103 10.2106/JBJS.J.00806 10.1302/0301-620X.102B2.BJJ-2019-0697.R2 10.5604/01.3001.0009.8980 10.1097/BOT.0000000000001488 10.3109/17453674.2012.678799 10.1056/NEJMra053077 10.3109/03093648509164708 10.1016/j.cmpb.2017.03.005 10.1002/jor.23352 10.1136/bmjopen-2016-013508 10.1007/s11999-013-3381-0 10.2106/JBJS.RVW.19.00043 10.1002/ar.24138 10.3109/17453674.2014.919559 10.1007/s00113-017-0331-4 10.1097/01.blo.0000246541.41951.20 |
| ContentType | Journal Article |
| Copyright | 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC. |
| Copyright_xml | – notice: 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC – notice: 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC. |
| DBID | AAYXX CITATION NPM 7X8 |
| DOI | 10.1002/jor.25247 |
| DatabaseName | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitleList | CrossRef PubMed MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 1554-527X |
| EndPage | 2075 |
| ExternalDocumentID | 34910325 10_1002_jor_25247 JOR25247 |
| Genre | article Journal Article |
| GrantInformation_xml | – fundername: U.S. Department of Veterans Affairs funderid: Grant # 1 I01 RX001208‐01 – fundername: U.S. Department of Veterans Affairs grantid: Grant # 1 I01 RX001208-01 |
| GroupedDBID | --- --K .3N .55 .GA .GJ .Y3 05W 0R~ 10A 1B1 1KJ 1L6 1OB 1OC 1ZS 1~5 24P 29L 31~ 33P 3SF 3V. 3WU 4.4 4G. 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5VS 66C 7-5 702 7PT 7X7 8-0 8-1 8-3 8-4 8-5 88E 88I 8AF 8FI 8FJ 8R4 8R5 8UM 930 A01 A03 AAEDT AAESR AAEVG AAHHS AAHQN AAIPD AALRI AAMNL AANHP AANLZ AAONW AAQFI AAQQT AAQXK AASGY AAXRX AAXUO AAYCA AAZKR ABCQN ABCUV ABEML ABIJN ABJNI ABMAC ABPVW ABQWH ABUWG ABWVN ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACFBH ACGFO ACGFS ACGOD ACGOF ACIUM ACMXC ACPOU ACRPL ACSCC ACXBN ACXQS ACYXJ ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADMUD ADNMO ADZMN AEEZP AEGXH AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFFPM AFGKR AFKRA AFPWT AFWVQ AFZJQ AHBTC AHEFC AHMBA AIACR AIAGR AITYG AIURR AIWBW AJBDE ALAGY ALIPV ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZQEC AZVAB BAFTC BDRZF BENPR BFHJK BHBCM BMXJE BPHCQ BQCPF BROTX BRXPI BVXVI BY8 C45 CCPQU CS3 D-6 D-7 D-E D-F DCZOG DPXWK DR1 DR2 DRFUL DRMAN DRSTM DU5 DWQXO EBD EBS EJD EMOBN F00 F01 F04 F5P FDB FEDTE FGOYB FUBAC FYUFA G-S G.N GNP GNUQQ GODZA H.X HBH HCIFZ HF~ HGLYW HHY HHZ HMCUK HVGLF HZ~ IHE IX1 J0M JPC KBYEO LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M1P M2P M41 M56 MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ NNB NQ- O66 O9- OIG OVD P2P P2W P2X P2Z P4B P4D PALCI PQQKQ PROAC PSQYO Q.N Q11 Q2X QB0 QRW R.K R2- RIG RIWAO RJQFR RNS ROL RPZ RWI RWL RWR RX1 RXW RYL SAMSI SEW SSZ SUPJJ SV3 TAE TEORI UB1 UKHRP UPT V2E V8K W8V W99 WBKPD WIB WIH WIJ WIK WIN WJL WNSPC WOHZO WQJ WRC WXI WXSBR WYB WYISQ X7M XG1 XV2 YCJ YQT ZGI ZXP ZZTAW ~IA ~WT 9DU AAMMB AAYXX ACVFH ADCNI AEFGJ AEUPX AEYWJ AFFHD AFPUW AGHNM AGQPQ AGXDD AGYGG AIDQK AIDYY AIGII AIQQE CITATION O8X PHGZM PHGZT PJZUB PPXIY NPM 7X8 |
| ID | FETCH-LOGICAL-c3257-1418d2a9ff14f798880c321475b44f2da7e49aac5728c4b6f6e71c6acd037eea3 |
| IEDL.DBID | WIN |
| ISICitedReferencesCount | 3 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000734675100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0736-0266 1554-527X |
| IngestDate | Fri Sep 05 10:00:40 EDT 2025 Wed Feb 19 02:28:18 EST 2025 Sat Nov 29 05:33:19 EST 2025 Tue Nov 18 21:54:28 EST 2025 Wed Jan 22 16:23:32 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 9 |
| Keywords | amputation bone remodeling percutaneous osseointegration prosthesis |
| Language | English |
| License | 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c3257-1418d2a9ff14f798880c321475b44f2da7e49aac5728c4b6f6e71c6acd037eea3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0003-0855-4182 0000-0002-6334-9803 0000-0001-7743-4323 |
| PMID | 34910325 |
| PQID | 2610408445 |
| PQPubID | 23479 |
| PageCount | 11 |
| ParticipantIDs | proquest_miscellaneous_2610408445 pubmed_primary_34910325 crossref_citationtrail_10_1002_jor_25247 crossref_primary_10_1002_jor_25247 wiley_primary_10_1002_jor_25247_JOR25247 |
| PublicationCentury | 2000 |
| PublicationDate | September 2022 |
| PublicationDateYYYYMMDD | 2022-09-01 |
| PublicationDate_xml | – month: 09 year: 2022 text: September 2022 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Journal of orthopaedic research |
| PublicationTitleAlternate | J Orthop Res |
| PublicationYear | 2022 |
| References | 2017; 5 2012; 83 2017; 7 2021; 6 1989; 4 2015; 6 2019; 33 1985; 9 2019; 37 2020; 80 2017; 89 2019; 14 2019; 302 2016; 97 2019; 19 2008; 79 2005 2008; 32 2012; 15 2012; 37 2014; 85 1979; 292 2011; 19 2019; 182 2012; 55 2014; 472 2006; 354 2006; 453 2007; 14 2020; 8 2012; 295 2020; 73 2020 2017; 35 1999; 14 2011; 42 2001; 38 2017; 120 2013 2017; 143 2010; 92 2020; 102‐B e_1_2_8_28_1 e_1_2_8_29_1 e_1_2_8_24_1 e_1_2_8_25_1 e_1_2_8_46_1 e_1_2_8_26_1 e_1_2_8_27_1 e_1_2_8_2_1 e_1_2_8_5_1 e_1_2_8_4_1 e_1_2_8_7_1 e_1_2_8_9_1 e_1_2_8_43_1 e_1_2_8_21_1 e_1_2_8_42_1 e_1_2_8_22_1 e_1_2_8_45_1 e_1_2_8_23_1 e_1_2_8_44_1 e_1_2_8_41_1 e_1_2_8_40_1 e_1_2_8_17_1 e_1_2_8_18_1 e_1_2_8_39_1 e_1_2_8_19_1 e_1_2_8_13_1 e_1_2_8_36_1 e_1_2_8_14_1 e_1_2_8_35_1 Taylor CE (e_1_2_8_32_1) 2020 e_1_2_8_38_1 Brånemark P‐I (e_1_2_8_6_1) 2005 e_1_2_8_16_1 e_1_2_8_37_1 Ontario H (e_1_2_8_20_1) 2019; 19 Reif TJ (e_1_2_8_15_1) 2021; 6 e_1_2_8_10_1 e_1_2_8_31_1 e_1_2_8_11_1 e_1_2_8_34_1 e_1_2_8_12_1 e_1_2_8_33_1 Brånemark R (e_1_2_8_8_1) 2001; 38 Mak AF (e_1_2_8_3_1) 2001; 38 e_1_2_8_30_1 |
| References_xml | – volume: 102‐B start-page: 162 issue: 2 year: 2020 end-page: 169 article-title: Periprosthetic osseointegration fractures are infrequent and management is familiar publication-title: Bone Joint J – volume: 97 start-page: 1053 issue: 7 year: 2016 end-page: 1063 article-title: Survey of U.S. practitioners on the validity of the medicare functional classification level system and utility of clinical outcome measures for aiding K‐level assignment publication-title: Arch Phys Med Rehabil – volume: 85 start-page: 442 issue: 4 year: 2014 end-page: 445 article-title: Retrieved bone‐anchored percutaneous amputation prosthesis showing maintained osseointegration after 11 years‐a case report publication-title: Acta Orthop – year: 2005 – volume: 453 start-page: 64 year: 2006 end-page: 74 article-title: New femoral designs ‐ do they influence stress shielding? publication-title: Clin Orthop Relat Res – volume: 472 start-page: 2957 issue: 10 year: 2014 end-page: 2965 article-title: Progression of bone ingrowth and attachment strength for stability of percutaneous osseointegrated prostheses publication-title: Clin Orthop Relat Res – volume: 42 start-page: 551 issue: 6 year: 2011 end-page: 555 article-title: The biology of fracture healing publication-title: Injury – volume: 7 issue: 3 year: 2017 article-title: Single‐stage osseointegrated reconstruction and rehabilitation of lower limb amputees: the Osseointegration Group of Australia Accelerated Protocol‐2 (OGAAP‐2) for a prospective cohort study publication-title: BMJ Open – volume: 354 start-page: 2250 issue: 21 year: 2006 end-page: 2261 article-title: Mechanisms of disease—bone quality—the material and structural basis of bone strength and fragility publication-title: N Engl J Med – volume: 9 start-page: 69 issue: 2 year: 1985 end-page: 78 article-title: A review of employment patterns of industrial amputees—factors influencing rehabilitation publication-title: Prosthet Orthot Int – volume: 38 start-page: 175 issue: 2 year: 2001 end-page: 181 article-title: Osseointegration in skeletal reconstruction and rehabilitation: a review publication-title: J Rehabil Res Dev – volume: 37 start-page: 2645 issue: 12 year: 2019 end-page: 2654 article-title: Analysis of the stomal microbiota of a percutaneous osseointegrated prosthesis: a longitudinal prospective cohort study publication-title: J Orthop Res – volume: 14 issue: 10 year: 2019 article-title: Variation in bone response to the placement of percutaneous osseointegrated endoprostheses: a 24‐month follow‐up in sheep publication-title: PLoS ONE – volume: 8 issue: 3 year: 2020 article-title: Osseointegration for amputees: current implants, techniques, and future directions publication-title: JBJS Rev – volume: 19 start-page: 1343 issue: 11 year: 2011 end-page: 1348 article-title: Feasibility of bone density evaluation using plain digital radiography publication-title: Osteoarthritis Cartilage – volume: 120 start-page: 285 issue: 4 year: 2017 end-page: 292 article-title: Osseointegrated prostheses for rehabilitation following amputation publication-title: Der Unfallchirurg – volume: 182 year: 2019 article-title: A review on multiplatform evaluations of semi‐automatic open‐source based image segmentation for cranio‐maxillofacial surgery publication-title: Comput Methods Programs Biomed – volume: 295 start-page: 1437 issue: 9 year: 2012 end-page: 1445 article-title: Cortical bone response to the presence of load‐bearing percutaneous osseointegrated prostheses publication-title: Anat Rec – volume: 92 start-page: 180 issue: Suppl 2 year: 2010 end-page: 186 article-title: Transcutaneous, distal femoral, intramedullary attachment for above‐the‐knee prostheses: an endo‐exo device publication-title: J Bone Joint Surg Am – volume: 302 start-page: 1709 issue: 10 year: 2019 end-page: 1717 article-title: Sex and laterality differences in medullary humerus morphology publication-title: Anat Rec (Hoboken) – volume: 143 start-page: 171 year: 2017 end-page: 184 article-title: Semi‐automatic segmentation of femur based on harmonic barrier publication-title: Comput Methods Programs Biomed – volume: 89 start-page: 57 issue: 2 year: 2017 end-page: 61 article-title: Analysis of selected factors determining quality of life in patients after lower limb amputation—a review article publication-title: Pol J Surg – volume: 79 start-page: 78 issue: 1 year: 2008 end-page: 85 article-title: Forearm bone‐anchored amputation prosthesis: a case study on the osseointegration publication-title: Acta Orthop – volume: 14 start-page: 355 issue: 3 year: 1999 end-page: 368 article-title: Implant fixation by bone ingrowth publication-title: J Arthroplasty – volume: 55 start-page: 401 issue: 6 year: 2012 end-page: 407 article-title: Limitations of conventional radiographs in the assessment of acetabular defects following total hip arthroplasty publication-title: Can J Surg – volume: 35 start-page: 1113 issue: 5 year: 2017 end-page: 1122 article-title: Effect of load on the bone around bone‐anchored amputation prostheses publication-title: J Orthop Res – volume: 38 start-page: 161 issue: 2 year: 2001 end-page: 174 article-title: State‐of‐the‐art research in lower‐limb prosthetic biomechanics‐socket interface: a review publication-title: J Rehabil Res Dev – volume: 19 start-page: 1 issue: 7 year: 2019 end-page: 126 article-title: Osseointegrated prosthetic implants for people with lower‐limb amputation: a health technology assessment publication-title: Ont Health Technol Assess Ser – volume: 6 start-page: 122 year: 2015 article-title: Modalities for visualization of cortical bone remodeling: the past, present, and future publication-title: Front Endocrinol (Lausanne) – volume: 6 start-page: 3 year: 2021 article-title: Early experience with femoral and tibial bone‐anchored osseointegration prostheses publication-title: JB JS Open Access – volume: 80 start-page: 49 year: 2020 end-page: 55 article-title: Estimated forces and moments experienced by osseointegrated endoprostheses for lower extremity amputees publication-title: Gait Posture – volume: 83 start-page: 121 issue: 2 year: 2012 end-page: 128 article-title: Stable fixation of an osseointegated implant system for above‐the‐knee amputees: titel RSA and radiographic evaluation of migration and bone remodeling in 55 cases publication-title: Acta Orthop – volume: 292 start-page: 147 issue: 1390 year: 1979 end-page: 156 – volume: 15 start-page: 167 year: 2012 end-page: 175 article-title: Simulated bone remodeling around two types of osseointegrated implants for direct fixation of upper‐leg prostheses publication-title: J Mech Behav Biomed Mater – volume: start-page: year: 2020 article-title: Cortical and medullary morphology of the tibia publication-title: Anat Rec (Hoboken) – volume: 32 start-page: 29 issue: 1 year: 2008 end-page: 41 article-title: Osseointegrated trans‐femoral amputation prostheses: prospective results of general and condition‐specific quality of life in 18 patients at 2‐year follow‐up publication-title: Prosthet Orthot Int – volume: 14 start-page: 133 issue: 2 year: 2007 end-page: 137 article-title: A tibial‐based coordinate system for three‐dimensional data publication-title: Knee – volume: 35 start-page: 1237 issue: 6 year: 2017 end-page: 1241 article-title: Periprosthetic cortical bone remodeling in patients with an osseointegrated leg prosthesis publication-title: J Orthop Res – volume: 33 start-page: e303 issue: 8 year: 2019 end-page: e308 article-title: Radiographic evaluation of bone remodeling around osseointegration implants among transfemoral amputees publication-title: J Orthop Trauma – volume: 5 issue: 10 year: 2017 article-title: Osseointegration for lower‐limb amputation: a systematic review of clinical outcomes publication-title: JBJS Rev – volume: 4 start-page: 3 issue: 1 year: 1989 end-page: 11 article-title: The direct examination of three‐dimensional bone architecture in vitro by computed tomography publication-title: J Bone Miner Res – volume: 37 start-page: E571 issue: 10 year: 2012 end-page: E580 article-title: Host bone response to polyetheretherketone versus porous tantalum implants for cervical spinal fusion in a goat model publication-title: Spine – volume: 73 start-page: 201 year: 2020 end-page: 212 article-title: Load response of an osseointegrated implant used in the treatment of unilateral transfemoral amputation: an early implant loosening case study publication-title: Clin Biomech (Bristol, Avon) – year: 2013 – ident: e_1_2_8_18_1 doi: 10.1016/j.injury.2011.03.031 – ident: e_1_2_8_46_1 doi: 10.1016/j.gaitpost.2020.05.018 – ident: e_1_2_8_19_1 doi: 10.1016/j.jmbbm.2012.06.015 – ident: e_1_2_8_25_1 doi: 10.1016/j.joca.2011.08.003 – ident: e_1_2_8_14_1 doi: 10.1016/j.clinbiomech.2020.01.017 – ident: e_1_2_8_43_1 doi: 10.1016/j.cmpb.2019.105102 – volume-title: The Osseointegration Book: From Calvarium to Calcaneus year: 2005 ident: e_1_2_8_6_1 – ident: e_1_2_8_11_1 doi: 10.1080/03093640701553922 – ident: e_1_2_8_37_1 doi: 10.1002/ar.22533 – ident: e_1_2_8_21_1 doi: 10.1002/jor.24421 – ident: e_1_2_8_29_1 doi: 10.3389/fendo.2015.00122 – start-page: year: 2020 ident: e_1_2_8_32_1 article-title: Cortical and medullary morphology of the tibia publication-title: Anat Rec (Hoboken) – ident: e_1_2_8_7_1 doi: 10.2106/JBJS.RVW.17.00037 – ident: e_1_2_8_22_1 – ident: e_1_2_8_23_1 doi: 10.1503/cjs.000511 – ident: e_1_2_8_39_1 doi: 10.1080/17453670710014806 – volume: 38 start-page: 175 issue: 2 year: 2001 ident: e_1_2_8_8_1 article-title: Osseointegration in skeletal reconstruction and rehabilitation: a review publication-title: J Rehabil Res Dev – ident: e_1_2_8_36_1 doi: 10.1371/journal.pone.0221850 – volume: 6 start-page: 3 year: 2021 ident: e_1_2_8_15_1 article-title: Early experience with femoral and tibial bone‐anchored osseointegration prostheses publication-title: JB JS Open Access – ident: e_1_2_8_24_1 doi: 10.1098/rsta.1979.0048 – ident: e_1_2_8_33_1 doi: 10.1016/j.apmr.2016.02.024 – ident: e_1_2_8_34_1 doi: 10.1097/BRS.0b013e318240f981 – volume: 19 start-page: 1 issue: 7 year: 2019 ident: e_1_2_8_20_1 article-title: Osseointegrated prosthetic implants for people with lower‐limb amputation: a health technology assessment publication-title: Ont Health Technol Assess Ser – ident: e_1_2_8_27_1 doi: 10.1002/jor.23376 – ident: e_1_2_8_38_1 doi: 10.1016/S0883-5403(99)90063-3 – ident: e_1_2_8_30_1 doi: 10.1016/j.knee.2006.11.001 – ident: e_1_2_8_28_1 doi: 10.1002/jbmr.5650040103 – ident: e_1_2_8_9_1 doi: 10.2106/JBJS.J.00806 – ident: e_1_2_8_13_1 doi: 10.1302/0301-620X.102B2.BJJ-2019-0697.R2 – ident: e_1_2_8_5_1 doi: 10.5604/01.3001.0009.8980 – ident: e_1_2_8_26_1 doi: 10.1097/BOT.0000000000001488 – ident: e_1_2_8_41_1 doi: 10.3109/17453674.2012.678799 – volume: 38 start-page: 161 issue: 2 year: 2001 ident: e_1_2_8_3_1 article-title: State‐of‐the‐art research in lower‐limb prosthetic biomechanics‐socket interface: a review publication-title: J Rehabil Res Dev – ident: e_1_2_8_16_1 doi: 10.1056/NEJMra053077 – ident: e_1_2_8_2_1 doi: 10.3109/03093648509164708 – ident: e_1_2_8_44_1 doi: 10.1016/j.cmpb.2017.03.005 – ident: e_1_2_8_45_1 doi: 10.1002/jor.23352 – ident: e_1_2_8_10_1 doi: 10.1136/bmjopen-2016-013508 – ident: e_1_2_8_35_1 doi: 10.1007/s11999-013-3381-0 – ident: e_1_2_8_12_1 doi: 10.2106/JBJS.RVW.19.00043 – ident: e_1_2_8_31_1 doi: 10.1002/ar.24138 – ident: e_1_2_8_42_1 – ident: e_1_2_8_40_1 doi: 10.3109/17453674.2014.919559 – ident: e_1_2_8_4_1 doi: 10.1007/s00113-017-0331-4 – ident: e_1_2_8_17_1 doi: 10.1097/01.blo.0000246541.41951.20 |
| SSID | ssj0007128 |
| Score | 2.3998568 |
| Snippet | Osseointegration (OI) is being used for the direct skeletal attachment of prosthetic limbs using an intramedullary stem that extends percutaneously from the... |
| SourceID | proquest pubmed crossref wiley |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 2065 |
| SubjectTerms | amputation bone remodeling osseointegration percutaneous prosthesis |
| Title | Use of computer tomography imaging for analyzing bone remodeling around a percutaneous osseointegrated implant |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fjor.25247 https://www.ncbi.nlm.nih.gov/pubmed/34910325 https://www.proquest.com/docview/2610408445 |
| Volume | 40 |
| WOSCitedRecordID | wos000734675100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVWIB databaseName: Wiley Online Library Free Content customDbUrl: eissn: 1554-527X dateEnd: 20241209 omitProxy: false ssIdentifier: ssj0007128 issn: 0736-0266 databaseCode: WIN dateStart: 20010101 isFulltext: true titleUrlDefault: https://onlinelibrary.wiley.com providerName: Wiley-Blackwell – providerCode: PRVWIB databaseName: Wiley Online Library Full Collection 2020 customDbUrl: eissn: 1554-527X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0007128 issn: 0736-0266 databaseCode: DRFUL dateStart: 20010101 isFulltext: true titleUrlDefault: https://onlinelibrary.wiley.com providerName: Wiley-Blackwell |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT9wwEB4B5cClD9HH9rEyiAOXlMR2Ykc9IeiqrdCCEKvuLRo7EwkEm1V2t4f--tpONggVpEq9xYozcmY843Hi-T6Ag6rkpchIR8IYFUmTqgiNEhGqDDVmMYoyFAqfqfFYT6f5xQZ8WdfCtPgQ_Qc37xkhXnsHR7M4ugcNvambzzzl0leSJzI45c_v4z4KqyTwqroZ7A_ZZtkaVSjmR_2TD9eivxLMh_lqWHBGL_5rqC_heZdnsuN2YryCDZrtwmyyIFZXzHZUDmxZ33WQ1ez6LvAVMZfEMvRIJb99y9QzYg0FvhzfxsbTMDFkc2rsyiWWVK8WzL0c1T3wROlkzW-dxV7DZPT16uRb1BEuRFY4142cGnXJMa-qRFYeyEzHNhAZpUbKipeoSOaINlVcW2myKiOV2AxtGQtFhOINbM3cuN4Bw5wSK5y5KSklWW0qhUZjbo22Oel4AIdr1Re2QyP3pBi3RYujzAuntCIobQD7fdd5C8HxWKe9tf0K5yD-r0ergsJtEV2g0lKmA3jbGrYXI2TuAQXdncNgv6flFz_OL8PF-3_v-gF2uC-WCCfSPsLWslnRJ9i2v5bXi2YIm2qqh_Ds9HI0ORuGyfsHF5_zcQ |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB6VLRJcoIjXQh8GceglNLGd2JF6QW1XBZYFVV2pt2jsTKSidrPK7nLg12M72aAKKlXqLVYmI2ce9sSxvw_gQ1XyUmSkI2GMiqRJVYRGiQhVhhqzGEUZDgqP1WSiLy7yHxtwuD4L0-JD9AtuPjPCeO0T3C9IH_xFDf1ZNx95yqV6AJvShVE6gM3js9F03I_EKgncqi6K_UbbLFsjC8X8oH_45nz0T5F5s2YNk87o6f26uwVPumKTfWqj4xls0Ow5zKYLYnXFbMfnwJb1dYdbzS6vA2kRc5UsQw9X8tu3TD0j1lAgzfFtbDwXE0M2p8auXHVJ9WrB3NtR3aNPlE7X_Mq57QVMRyfnR6dRx7oQWeHyN0pkokuOeVUlsvJoZjq2gc0oNVJWvERFMke0qeLaSpNVGanEZmjLWCgiFC9hMHP9eg0Mc0qscD6npJRktakUGo25NdrmpOMh7K9tX9gOktwzY1wVLZgyL5zRimC0IbzvRectDsf_hN6tHVi4LPG_PloTFO470Y1WWsp0CK9az_ZqhMw9qqC7sx8ceLv-4sv3s3Dx5u6ie_Do9PzbuBh_nnx9C4-5Pz0Rtqhtw2DZrGgHHtpfy8tFs9tF7x-_HfY1 |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1La9wwEB7SpJRe-qBtsn2qpYdc3NiSLMnQS0i69LFsQ-hCbkaPESQk68W720N-fSTZ6xLaQqE3C4-FPA9pZGu-D-C9d9QxgSpjxsiMm1Jm2kiWaSm00iLXzKVC4YmcTtXZWXWyBR83tTAdPsTwwS1GRpqvY4DjwvmDX6ihF037gZaUyzuww8tKhLDcOT4dzybDTCyLxK0avDgetBVigyyU04Ph4dvr0W9J5u2cNS0644f_N9xH8KBPNslh5x2PYQvnT2A-WyJpPLE9nwNZNVc9bjU5v0qkRSRkskRHuJLr2DLNHEmLiTQntnUbuZiIJgts7Tpkl9islyS8HTYD-oQLfS0ug9mewmz86cfR56xnXcgsC_GbFbxQjurK-4L7iGamcpvYjErDuadOS-SV1raUVFluhBcoCyu0dTmTiJo9g-15GNceEF1hYVmwORaOo1XGS22UrqxRtkKVj2B_o_va9pDkkRnjsu7AlGkdlFYnpY3g3SC66HA4_iT0dmPAOkRJ_PXRqaAO-8QwWynOyxHsdpYdumG8iqiC4c5-MuDf-6-_fj9NF8__XfQN3Ds5HteTL9NvL-A-jcUT6YTaS9hetWt8BXftz9X5sn3dO-8NWvv1sA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Use+of+computer+tomography+imaging+for+analyzing+bone+remodeling+around+a+percutaneous+osseointegrated+implant&rft.jtitle=Journal+of+orthopaedic+research&rft.au=Wankier%2C+Zakary&rft.au=Taylor%2C+Carolyn&rft.au=Drew%2C+Alex&rft.au=Kubiak%2C+Erik&rft.date=2022-09-01&rft.eissn=1554-527X&rft_id=info:doi/10.1002%2Fjor.25247&rft_id=info%3Apmid%2F34910325&rft.externalDocID=34910325 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0736-0266&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0736-0266&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0736-0266&client=summon |