Pre‐transplant short physical performance battery: Response to pre‐habilitation and relationship to pre‐ and early post–lung‐transplant outcomes
Purpose To evaluate whether the short physical performance battery (SPPB) pre‐lung transplant (LTx) was responsive to pre‐habilitation and predicted pre‐ and early post‐transplant outcomes. Methods A retrospective study of LTx candidates accepted for transplant between 2016 and 2017. SPPB was catego...
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| Vydané v: | Clinical transplantation Ročník 34; číslo 12; s. e14095 - n/a |
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| Hlavní autori: | , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
Denmark
01.12.2020
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| ISSN: | 0902-0063, 1399-0012, 1399-0012 |
| On-line prístup: | Získať plný text |
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| Shrnutí: | Purpose
To evaluate whether the short physical performance battery (SPPB) pre‐lung transplant (LTx) was responsive to pre‐habilitation and predicted pre‐ and early post‐transplant outcomes.
Methods
A retrospective study of LTx candidates accepted for transplant between 2016 and 2017. SPPB was categorized as frail/pre‐frail (≤9/12) and non‐frail (≥10/12).
Results
150 patients had LTx assessment SPPB data (53% male, 61 [52‐67] years, 59% had interstitial lung disease (ILD), 26% frail/pre‐frail). 131 (87%) underwent transplant by December 31, 2018. Adjusting for age, sex, diagnosis and Canadian transplant listing urgency, and frailty/pre‐frailty at LTx assessment was associated with a lower 6MWD pre‐transplant [−89 meters 95%CI (−125 to −53), P < .0001]. 62 patients underwent six weeks of pre‐habilitation. SPPB increased (11 [10‐12) vs. 12 [11‐12], P = .01) reflected in the chair stand component (11.4 ± 4.4 vs. 9.8 ± 2.8 seconds, P = .007), with larger improvements in the frail/pre‐frail group. A frail/pre‐frail SPPB closest to the time of transplant was associated with a lower 6MWD [−77 m 95%CI (−128 to −25), P = .004] but not with hospital length of stay or gait aid use three months post‐transplant.
Conclusions
Frailty/pre‐frailty was associated with a decreased 6MWD pre‐ and post‐transplant. The SPPB increased following pre‐habilitation, which may reflect increased lower extremity strength. |
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| Bibliografia: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 0902-0063 1399-0012 1399-0012 |
| DOI: | 10.1111/ctr.14095 |