Allele and haplotype frequencies of 11 HLA loci in Koreans by next‐generation sequencing

Data on HLA genotype distribution, including DQA1 and DPA1, in the Korean population are limited. We aimed to investigate the allele and haplotype frequencies of 11 HLA loci in 339 Korean subjects using next‐generation sequencing (NGS)‐based HLA typing. A total of 339 samples from unrelated healthy...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:HLA Ročník 101; číslo 6; s. 602 - 612
Hlavní autoři: Jung, Kiwook, Kim, Jisoo G., Shin, Sue, Roh, Eun Youn, Hong, Yun Ji, Song, Eun Young
Médium: Journal Article
Jazyk:angličtina
Vydáno: Oxford, UK Blackwell Publishing Ltd 01.06.2023
Témata:
allele frequency
Alleles
East Asian People
Gene Frequency
Haplotypes
High-Throughput Nucleotide Sequencing
Histocompatibility Antigens Class II - genetics
HLA population genetics
HLA-DRB1 Chains - genetics
Humans
Korean population
next‐generation sequencing
Korean population
next-generation sequencing
HLA population genetics
allele frequency
ISSN:2059-2302, 2059-2310, 2059-2310
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Abstract Data on HLA genotype distribution, including DQA1 and DPA1, in the Korean population are limited. We aimed to investigate the allele and haplotype frequencies of 11 HLA loci in 339 Korean subjects using next‐generation sequencing (NGS)‐based HLA typing. A total of 339 samples from unrelated healthy subjects were genotyped for HLA‐A, ‐B, ‐C, ‐DRB1, ‐DRB3, ‐DRB4, ‐DRB5, ‐DQB1, ‐DQA1, ‐DPB1, and ‐DPA1 using two different NGS‐based HLA typing kits (166 tested using the NGSgo‐MX11‐3 kit [GenDx, Netherlands] and 173 by the AllType NGS 11 Loci Amplification kit [One Lambda, USA]). PyPop software was used to estimate allele and haplotype frequencies and linkage disequilibrium between the loci. Additionally, a principal component analysis was performed to compare the allele distribution of Koreans with that of other populations. A total of 214 HLA alleles (97 class I and 117 class II alleles) were assigned. The most frequent alleles for each locus were A*24:02:01 (24.78%), B*15:01:01 (10.18%), C*01:02:01 (18.44%), DRB1*04:05:01 (9.59%), DRB3*02:02:01 (13.72%), DRB4*01:03:01 (25.81%), DRB5*01:01:01 (9.0%), DQA1*01:02:01 (16.96%), DQB1*03:01:01 (14.31%), DPA1*01:03:01 (44.4%), and DPB1*05:01:01 (35.1%), respectively. The most frequent haplotypes were A*33:03:01‐C*03:02:02‐B*58:01:01 for HLA class I (5.01%) and DRB1*04:05:01‐DQA1*03:03:01‐DQB1*04:01:01‐DPA1*02:02:02‐DPB1*05:01:01 for HLA class II (6.23%). The total allelic ambiguities by NGS were estimated to be minimal and considerably decreased compared with those by Sanger sequencing. The Japanese population had the most similar allele distribution to Koreans, followed by the Chinese population. Frequency data of 11 HLA loci in Koreans can provide essential data for population genetics and disease association studies.
AbstractList Data on HLA genotype distribution, including DQA1 and DPA1, in the Korean population are limited. We aimed to investigate the allele and haplotype frequencies of 11 HLA loci in 339 Korean subjects using next‐generation sequencing (NGS)‐based HLA typing. A total of 339 samples from unrelated healthy subjects were genotyped for HLA‐A, ‐B, ‐C, ‐DRB1, ‐DRB3, ‐DRB4, ‐DRB5, ‐DQB1, ‐DQA1, ‐DPB1, and ‐DPA1 using two different NGS‐based HLA typing kits (166 tested using the NGSgo‐MX11‐3 kit [GenDx, Netherlands] and 173 by the AllType NGS 11 Loci Amplification kit [One Lambda, USA]). PyPop software was used to estimate allele and haplotype frequencies and linkage disequilibrium between the loci. Additionally, a principal component analysis was performed to compare the allele distribution of Koreans with that of other populations. A total of 214 HLA alleles (97 class I and 117 class II alleles) were assigned. The most frequent alleles for each locus were A*24:02:01 (24.78%), B*15:01:01 (10.18%), C*01:02:01 (18.44%), DRB1*04:05:01 (9.59%), DRB3*02:02:01 (13.72%), DRB4*01:03:01 (25.81%), DRB5*01:01:01 (9.0%), DQA1*01:02:01 (16.96%), DQB1*03:01:01 (14.31%), DPA1*01:03:01 (44.4%), and DPB1*05:01:01 (35.1%), respectively. The most frequent haplotypes were A*33:03:01‐C*03:02:02‐B*58:01:01 for HLA class I (5.01%) and DRB1*04:05:01‐DQA1*03:03:01‐DQB1*04:01:01‐DPA1*02:02:02‐DPB1*05:01:01 for HLA class II (6.23%). The total allelic ambiguities by NGS were estimated to be minimal and considerably decreased compared with those by Sanger sequencing. The Japanese population had the most similar allele distribution to Koreans, followed by the Chinese population. Frequency data of 11 HLA loci in Koreans can provide essential data for population genetics and disease association studies.
Data on HLA genotype distribution, including DQA1 and DPA1, in the Korean population are limited. We aimed to investigate the allele and haplotype frequencies of 11 HLA loci in 339 Korean subjects using next-generation sequencing (NGS)-based HLA typing. A total of 339 samples from unrelated healthy subjects were genotyped for HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, -DQB1, -DQA1, -DPB1, and -DPA1 using two different NGS-based HLA typing kits (166 tested using the NGSgo-MX11-3 kit [GenDx, Netherlands] and 173 by the AllType NGS 11 Loci Amplification kit [One Lambda, USA]). PyPop software was used to estimate allele and haplotype frequencies and linkage disequilibrium between the loci. Additionally, a principal component analysis was performed to compare the allele distribution of Koreans with that of other populations. A total of 214 HLA alleles (97 class I and 117 class II alleles) were assigned. The most frequent alleles for each locus were A*24:02:01 (24.78%), B*15:01:01 (10.18%), C*01:02:01 (18.44%), DRB1*04:05:01 (9.59%), DRB3*02:02:01 (13.72%), DRB4*01:03:01 (25.81%), DRB5*01:01:01 (9.0%), DQA1*01:02:01 (16.96%), DQB1*03:01:01 (14.31%), DPA1*01:03:01 (44.4%), and DPB1*05:01:01 (35.1%), respectively. The most frequent haplotypes were A*33:03:01-C*03:02:02-B*58:01:01 for HLA class I (5.01%) and DRB1*04:05:01-DQA1*03:03:01-DQB1*04:01:01-DPA1*02:02:02-DPB1*05:01:01 for HLA class II (6.23%). The total allelic ambiguities by NGS were estimated to be minimal and considerably decreased compared with those by Sanger sequencing. The Japanese population had the most similar allele distribution to Koreans, followed by the Chinese population. Frequency data of 11 HLA loci in Koreans can provide essential data for population genetics and disease association studies.Data on HLA genotype distribution, including DQA1 and DPA1, in the Korean population are limited. We aimed to investigate the allele and haplotype frequencies of 11 HLA loci in 339 Korean subjects using next-generation sequencing (NGS)-based HLA typing. A total of 339 samples from unrelated healthy subjects were genotyped for HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, -DQB1, -DQA1, -DPB1, and -DPA1 using two different NGS-based HLA typing kits (166 tested using the NGSgo-MX11-3 kit [GenDx, Netherlands] and 173 by the AllType NGS 11 Loci Amplification kit [One Lambda, USA]). PyPop software was used to estimate allele and haplotype frequencies and linkage disequilibrium between the loci. Additionally, a principal component analysis was performed to compare the allele distribution of Koreans with that of other populations. A total of 214 HLA alleles (97 class I and 117 class II alleles) were assigned. The most frequent alleles for each locus were A*24:02:01 (24.78%), B*15:01:01 (10.18%), C*01:02:01 (18.44%), DRB1*04:05:01 (9.59%), DRB3*02:02:01 (13.72%), DRB4*01:03:01 (25.81%), DRB5*01:01:01 (9.0%), DQA1*01:02:01 (16.96%), DQB1*03:01:01 (14.31%), DPA1*01:03:01 (44.4%), and DPB1*05:01:01 (35.1%), respectively. The most frequent haplotypes were A*33:03:01-C*03:02:02-B*58:01:01 for HLA class I (5.01%) and DRB1*04:05:01-DQA1*03:03:01-DQB1*04:01:01-DPA1*02:02:02-DPB1*05:01:01 for HLA class II (6.23%). The total allelic ambiguities by NGS were estimated to be minimal and considerably decreased compared with those by Sanger sequencing. The Japanese population had the most similar allele distribution to Koreans, followed by the Chinese population. Frequency data of 11 HLA loci in Koreans can provide essential data for population genetics and disease association studies.
Data on HLA genotype distribution, including DQA1 and DPA1, in the Korean population are limited. We aimed to investigate the allele and haplotype frequencies of 11 HLA loci in 339 Korean subjects using next‐generation sequencing (NGS)‐based HLA typing. A total of 339 samples from unrelated healthy subjects were genotyped for HLA‐A, ‐B, ‐C, ‐DRB1, ‐DRB3, ‐DRB4, ‐DRB5, ‐DQB1, ‐DQA1, ‐DPB1, and ‐DPA1 using two different NGS‐based HLA typing kits (166 tested using the NGSgo‐MX11‐3 kit [GenDx, Netherlands] and 173 by the AllType NGS 11 Loci Amplification kit [One Lambda, USA]). PyPop software was used to estimate allele and haplotype frequencies and linkage disequilibrium between the loci. Additionally, a principal component analysis was performed to compare the allele distribution of Koreans with that of other populations. A total of 214 HLA alleles (97 class I and 117 class II alleles) were assigned. The most frequent alleles for each locus were A*24:02:01 (24.78%), B*15:01:01 (10.18%), C*01:02:01 (18.44%), DRB1*04:05:01 (9.59%), DRB3*02:02:01 (13.72%), DRB4*01:03:01 (25.81%), DRB5*01:01:01 (9.0%), DQA1*01:02:01 (16.96%), DQB1*03:01:01 (14.31%), DPA1*01:03:01 (44.4%), and DPB1*05:01:01 (35.1%), respectively. The most frequent haplotypes were A*33:03:01‐C*03:02:02‐B*58:01:01 for HLA class I (5.01%) and DRB1*04:05:01‐DQA1*03:03:01‐DQB1*04:01:01‐DPA1*02:02:02‐DPB1*05:01:01 for HLA class II (6.23%). The total allelic ambiguities by NGS were estimated to be minimal and considerably decreased compared with those by Sanger sequencing. The Japanese population had the most similar allele distribution to Koreans, followed by the Chinese population. Frequency data of 11 HLA loci in Koreans can provide essential data for population genetics and disease association studies.
Author Kim, Jisoo G.
Roh, Eun Youn
Song, Eun Young
Shin, Sue
Hong, Yun Ji
Jung, Kiwook
Author_xml – sequence: 1
  givenname: Kiwook
  orcidid: 0000-0001-8411-7473
  surname: Jung
  fullname: Jung, Kiwook
  organization: Chungbuk National University Hospital
– sequence: 2
  givenname: Jisoo G.
  surname: Kim
  fullname: Kim, Jisoo G.
  organization: Seoul National University College of Medicine
– sequence: 3
  givenname: Sue
  surname: Shin
  fullname: Shin, Sue
  organization: Seoul National University Boramae Medical Center
– sequence: 4
  givenname: Eun Youn
  surname: Roh
  fullname: Roh, Eun Youn
  organization: Seoul National University Boramae Medical Center
– sequence: 5
  givenname: Yun Ji
  surname: Hong
  fullname: Hong, Yun Ji
  email: aeiea@snu.ac.kr
  organization: Seoul National University Bundang Hospital
– sequence: 6
  givenname: Eun Young
  surname: Song
  fullname: Song, Eun Young
  email: eysong1@snu.ac.kr
  organization: Seoul National University College of Medicine
BackLink https://www.ncbi.nlm.nih.gov/pubmed/36719349$$D View this record in MEDLINE/PubMed
BookMark eNp1kD1OAzEQhS0UxE9IwQWQSyiSeNbxOltGCAgigiY0NJZ3dxYsOXawN4J0HIEzchI2fxQIXjNTfO-N5h2TlvMOCTkF1oNG_Vq7HgyyIdsjRwkTWTfhwFo_O0sOSSdGk7MkzSRLZXZADnkqIeOD7Ig8jaxFi1S7kr7oufX1co60Cvi6QFcYjNRXFICOJyNqfWGocfTOB9Qu0nxJHb7XXx-fz-gw6Np4R-PW6Z5PyH6lbcTOdrbJ4_XV9HLcnTzc3F6OJt2CJ4J1c55gUYm0FDJHqKTUKXCBGReAGkpkfIi8lDmkPE0RBUiBIhNDXQGXBQfeJueb3Hnwze1Yq5mJBVqrHfpFVImUwFcSDXq2RRf5DEs1D2amw1Lt-miA_gYogo8xYKUKU68fq4M2VgFTq9JVU7pal944Ln45dqF_sdv0N2Nx-T-opqP7jeMbSv6QVw
CitedBy_id crossref_primary_10_1111_tan_15806
crossref_primary_10_1111_tan_70382
crossref_primary_10_4274_forbes_galenos_2024_50375
crossref_primary_10_1111_tan_15121
crossref_primary_10_1111_tan_15451
crossref_primary_10_1111_tan_15230
crossref_primary_10_1111_tan_70339
crossref_primary_10_1111_tan_15291
crossref_primary_10_3390_jcm13123563
crossref_primary_10_1080_16583655_2025_2514284
crossref_primary_10_1111_tan_15810
crossref_primary_10_1111_tan_15467
crossref_primary_10_1111_tan_15511
crossref_primary_10_1111_tan_15522
crossref_primary_10_1111_tan_15124
crossref_primary_10_1111_tan_15630
crossref_primary_10_1111_tan_70369
crossref_primary_10_1002_advs_202409919
crossref_primary_10_1111_tan_70148
Cites_doi 10.1016/j.humimm.2014.04.001
10.1371/journal.pone.0253619
10.1038/s41588‐018‐0336‐0
10.1016/j.humimm.2009.02.002
10.1093/genetics/50.4.757
10.1034/j.1399‐0039.2002.590604.x
10.1111/tan.13811
10.1371/journal.pgen.0020064
10.1111/tri.12316
10.1016/j.humimm.2013.06.025
10.1111/tan.12966
10.1111/j.1600‐6143.2009.02701.x
10.1371/journal.pcbi.1005693
10.3389/fgene.2020.00383
10.1111/tan.14167
10.1097/TP.0000000000000220
10.1034/j.1399‐0039.2003.00089.x
10.3389/fimmu.2020.544768
10.1186/1479‐5876‐2‐30
10.1111/tan.13210
10.3343/ALM.2021.41.3.310
10.1016/j.humimm.2010.02.012
10.1111/iji.12067
10.1534/g3.118.200367
10.1007/BF02300753
10.1007/s00251‐014‐0757‐6
10.1111/nep.12772
10.1097/TP.0b013e3182a452a5
10.1093/nar/gkz950
10.1016/j.humimm.2018.09.005
10.1111/j.1399‐0039.2006.00769.x
10.1016/j.transproceed.2020.02.127
10.1034/j.1399‐0039.2002.600101.x
10.1016/j.humimm.2021.01.010
10.1016/j.humimm.2019.12.005
10.1086/282771
10.1111/tan.12007
10.1016/j.humimm.2008.05.001
10.1111/tan.13358
10.1016/j.jmoldx.2016.03.009
ContentType Journal Article
Copyright 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Copyright_xml – notice: 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
DOI 10.1111/tan.14980
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList
MEDLINE - Academic
CrossRef
MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: 7X8
  name: MEDLINE - Academic
  url: https://search.proquest.com/medline
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
EISSN 2059-2310
EndPage 612
ExternalDocumentID 36719349
10_1111_tan_14980
TAN14980
Genre researchArticle
Journal Article
GroupedDBID 0R~
1OC
33P
53G
5VS
8-0
8-1
8-4
AAEVG
AAHHS
AAHQN
AAIPD
AAMNL
AANLZ
AASGY
AAXRX
AAYCA
AAZKR
ABCUV
ABDBF
ABJNI
ABQWH
ABXGK
ACAHQ
ACCFJ
ACCZN
ACGFS
ACGOF
ACMXC
ACPOU
ACUHS
ACXBN
ACXQS
ADBBV
ADBTR
ADEOM
ADIZJ
ADKYN
ADMGS
ADOZA
ADXAS
ADZMN
ADZOD
AEEZP
AEIGN
AEIMD
AEQDE
AEUYR
AFBPY
AFFPM
AFGKR
AFPWT
AFWVQ
AFZJQ
AHBTC
AIACR
AITYG
AIURR
AIWBW
AJBDE
ALMA_UNASSIGNED_HOLDINGS
ALUQN
ALVPJ
AMBMR
AMYDB
AZFZN
BMXJE
BY8
C45
DCZOG
DRFUL
DRMAN
DRSTM
EAD
EAP
EBC
EBD
EBS
EJD
EMB
EMK
EMOBN
ESX
FUBAC
HGLYW
KBYEO
LATKE
LEEKS
LITHE
LOXES
LUTES
LYRES
MEWTI
MRFUL
MRMAN
MRSTM
MSFUL
MSMAN
MSSTM
MXFUL
MXMAN
MXSTM
O66
OVD
P2W
R9-
ROL
SUPJJ
SV3
TEORI
TUS
WIH
WIJ
WIK
WOHZO
WXSBR
AAMMB
AAYXX
AEFGJ
AEYWJ
AGHNM
AGXDD
AGYGG
AIDQK
AIDYY
CITATION
BFHJK
CGR
CUY
CVF
ECM
EIF
NPM
7X8
ID FETCH-LOGICAL-c3250-b32ecf56d57be1f77a6135e9351ea1de038e3d7b16366ee5175e5958af137c313
IEDL.DBID DRFUL
ISICitedReferencesCount 19
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000940946100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 2059-2302
2059-2310
IngestDate Thu Jul 10 19:08:21 EDT 2025
Thu Jan 02 22:52:06 EST 2025
Tue Nov 18 20:56:27 EST 2025
Sat Nov 29 01:51:47 EST 2025
Wed Jan 22 16:22:59 EST 2025
IsPeerReviewed true
IsScholarly true
Issue 6
Keywords Korean population
next-generation sequencing
HLA population genetics
allele frequency
Language English
License 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c3250-b32ecf56d57be1f77a6135e9351ea1de038e3d7b16366ee5175e5958af137c313
Notes Kiwook Jung and Jisoo G. Kim contributed equally to this study.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0001-8411-7473
PMID 36719349
PQID 2771333335
PQPubID 23479
PageCount 11
ParticipantIDs proquest_miscellaneous_2771333335
pubmed_primary_36719349
crossref_citationtrail_10_1111_tan_14980
crossref_primary_10_1111_tan_14980
wiley_primary_10_1111_tan_14980_TAN14980
PublicationCentury 2000
PublicationDate June 2023
2023-06-00
20230601
PublicationDateYYYYMMDD 2023-06-01
PublicationDate_xml – month: 06
  year: 2023
  text: June 2023
PublicationDecade 2020
PublicationPlace Oxford, UK
PublicationPlace_xml – name: Oxford, UK
– name: England
PublicationTitle HLA
PublicationTitleAlternate HLA
PublicationYear 2023
Publisher Blackwell Publishing Ltd
Publisher_xml – name: Blackwell Publishing Ltd
References 2002; 59
2012; 80
2019; 51
1983; 19
2021; 67
1964; 49
2013; 40
2020; 81
2017; 89
2014; 27
2020; 11
2004; 2
2006; 2
2016; 18
2014; 66
2021; 16
2018; 8
2021; 97
2009; 70
2020; 52
2020; 95
2020
2017; 13
2013; 96
2013; 74
2018; 92
2016; 21
2008; 69
2018; 91
2020; 48
2009; 9
2013
2021; 82
2021; 41
2003; 62
1972; 106
2007; 69
2014; 98
2018; 79
2014; 75
2010; 71
e_1_2_8_28_1
e_1_2_8_29_1
e_1_2_8_24_1
e_1_2_8_25_1
e_1_2_8_26_1
e_1_2_8_27_1
Nam M (e_1_2_8_43_1) 2021; 67
e_1_2_8_3_1
e_1_2_8_2_1
e_1_2_8_5_1
e_1_2_8_4_1
e_1_2_8_7_1
e_1_2_8_6_1
e_1_2_8_9_1
e_1_2_8_8_1
e_1_2_8_20_1
e_1_2_8_21_1
e_1_2_8_42_1
e_1_2_8_22_1
e_1_2_8_23_1
e_1_2_8_44_1
e_1_2_8_41_1
e_1_2_8_40_1
e_1_2_8_17_1
e_1_2_8_18_1
e_1_2_8_39_1
e_1_2_8_19_1
e_1_2_8_13_1
e_1_2_8_36_1
e_1_2_8_35_1
e_1_2_8_15_1
e_1_2_8_38_1
e_1_2_8_16_1
e_1_2_8_37_1
e_1_2_8_32_1
e_1_2_8_10_1
Korean Network for Organ Sharing (e_1_2_8_14_1) 2020
e_1_2_8_31_1
e_1_2_8_11_1
e_1_2_8_34_1
e_1_2_8_12_1
e_1_2_8_33_1
e_1_2_8_30_1
References_xml – start-page: 169
  year: 2013
  end-page: 184
– volume: 2
  start-page: 1
  year: 2004
  end-page: 6
  article-title: Ambiguous allele combinations in HLA class I and class II sequence‐based typing: when precise nucleotide sequencing leads to imprecise allele identification
  publication-title: J Transl Med
– volume: 41
  start-page: 310
  issue: 3
  year: 2021
  end-page: 317
  article-title: Identification of 8‐digit HLA‐A, ‐B, ‐C, and ‐DRB1 allele and haplotype frequencies in Koreans using the one lambda all type next‐generation sequencing kit
  publication-title: Ann Lab Med
– volume: 51
  start-page: 470
  issue: 3
  year: 2019
  end-page: 480
  article-title: Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population
  publication-title: Nat Genet
– volume: 16
  start-page: 1
  issue: 6
  year: 2021
  end-page: 14
  article-title: Allele and haplotype frequencies of human leukocyte antigen‐a, ‐B, ‐C, ‐DRB1, ‐DRB3/4/5, ‐DQA1, ‐DQB1, ‐DPA1, and ‐DPB1 by next generation sequencing‐based typing in Koreans in South Korea
  publication-title: PloS One
– volume: 92
  start-page: 199
  issue: 4
  year: 2018
  end-page: 205
  article-title: HLA common and well‐documented alleles in China
  publication-title: HLA
– volume: 21
  start-page: 31
  year: 2016
  end-page: 34
  article-title: Subclinical antibody‐mediated rejection due to anti‐human‐leukocyte‐antigen‐DR53 antibody accompanied by plasma cell‐rich acute rejection in a patient with cadaveric kidney transplantation
  publication-title: Nephrol Ther
– volume: 2
  start-page: 379
  issue: 4
  year: 2006
  end-page: 384
  article-title: Balancing selection and its effects on sequences in nearby genome regions
  publication-title: PLoS Genet
– volume: 48
  start-page: D948
  issue: D1
  year: 2020
  end-page: D955
  article-title: IPD‐IMGT/HLA Database
  publication-title: Nucleic Acids Res
– volume: 18
  start-page: 668
  issue: 5
  year: 2016
  end-page: 675
  article-title: Performance characteristics and validation of next‐generation sequencing for human leucocyte antigen typing
  publication-title: J Mol Diagn
– volume: 95
  start-page: 516
  issue: 6
  year: 2020
  end-page: 531
  article-title: Common, intermediate and well‐documented HLA alleles in world populations: CIWD version 3.0.0
  publication-title: HLA
– volume: 40
  start-page: 515
  issue: 6
  year: 2013
  end-page: 523
  article-title: HLA‐A, ‐B and ‐DRB1 polymorphism in koreans defined by sequence‐based typing of 4128 cord blood units
  publication-title: Int J Immunogenet
– volume: 66
  start-page: 153
  issue: 3
  year: 2014
  end-page: 160
  article-title: HLA variation reveals genetic continuity rather than population group structure in East Asia
  publication-title: Immunogenetics
– volume: 59
  start-page: 475
  issue: 6
  year: 2002
  end-page: 486
  article-title: HLA class II allele and haplotype frequencies in Koreans based on 107 families
  publication-title: Tissue Antigens
– volume: 75
  start-page: 703
  issue: 8
  year: 2014
  end-page: 708
  article-title: Early acute antibody‐mediated rejection of a negative flow crossmatch 3rd kidney transplant with exclusive disparity at HLA‐DP
  publication-title: Hum Immunol
– volume: 106
  start-page: 283
  issue: 949
  year: 1972
  end-page: 292
  article-title: Genetic distance between populations
  publication-title: Am Nat
– volume: 9
  start-page: 1826
  issue: 8
  year: 2009
  end-page: 1834
  article-title: Subclinical rejection in stable positive crossmatch kidney transplant patients: incidence and correlations
  publication-title: Am J Transplant
– volume: 67
  issue: 1
  year: 2021
  article-title: Evaluation of LabType‐SSO HLA typing for HLA‐A, ‐B, ‐C, ‐DRB1, and‐DQB1 loci
  publication-title: Clin Lab
– volume: 27
  start-page: 667
  issue: 7
  year: 2014
  end-page: 673
  article-title: DQ molecules are the principal stimulators of de novo donor‐specific antibodies in nonsensitized pediatric recipients receiving a first kidney transplant
  publication-title: Transpl Int
– volume: 8
  start-page: 2805
  issue: 8
  year: 2018
  end-page: 2815
  article-title: The effect of balancing selection on population differentiation: a study with HLA genes
  publication-title: G3 Genes Genomes Genet
– year: 2020
  article-title: Annual report of the transplant 2019
  publication-title: Seoul: Korean Network for Organ Sharing
– volume: 81
  start-page: 49
  issue: 2–3
  year: 2020
  end-page: 51
  article-title: High‐resolution allele frequencies for NGS based HLA‐A, B, C, DQB1 and DRB1 typing of 23,595 bone marrow donors recruited for the polish central potential unrelated bone marrow donor registry
  publication-title: Hum Immunol
– volume: 11
  start-page: 1
  year: 2020
  end-page: 10
  article-title: High‐resolution HLA typing of HLA‐A, ‐B, ‐C, ‐DRB1, and ‐DQB1 in Kinh Vietnamese by using next‐generation sequencing
  publication-title: Front Genet
– volume: 89
  start-page: 150
  issue: 3
  year: 2017
  end-page: 157
  article-title: Typing and copy number determination for HLA‐DRB3, ‐DRB4 and ‐DRB5 from next‐generation sequencing data
  publication-title: HLA
– volume: 74
  start-page: 1313
  issue: 10
  year: 2013
  end-page: 1320
  article-title: Six‐locus high resolution HLA haplotype frequencies derived from mixed‐resolution DNA typing for the entire US donor registry
  publication-title: Hum Immunol
– volume: 70
  start-page: 410
  issue: 6
  year: 2009
  end-page: 412
  article-title: Antibodies against HLA‐DQ α‐chain and their role in organ transplantation
  publication-title: Hum Immunol
– volume: 97
  start-page: 188
  issue: 3
  year: 2021
  end-page: 197
  article-title: Bin, et al. HLA‐A, ‐B, ‐C, ‐DRB1 allele and haplotype frequencies of the Korean population and performance characteristics of HLA typing by next‐generation sequencing
  publication-title: HLA
– volume: 82
  start-page: 478
  issue: 7
  year: 2021
  end-page: 487
  article-title: New challenges, new opportunities: next generation sequencing and its place in the advancement of HLA typing
  publication-title: Hum Immunol
– volume: 62
  start-page: 243
  issue: 3
  year: 2003
  end-page: 250
  article-title: Roles of HLA‐B, HLA‐C and HLA‐DPA1 incompatibilities in the outcome of unrelated stem‐cell transplantation
  publication-title: Tissue Antigens
– volume: 19
  start-page: 153
  issue: 2
  year: 1983
  end-page: 170
  article-title: Accuracy of estimated phylogenetic trees from molecular data
  publication-title: J Mol Evol
– volume: 98
  start-page: 157
  issue: 2
  year: 2014
  end-page: 166
  article-title: Epitope analysis of HLA‐DQ antigens: what does the antibody see?
  publication-title: Transplantation
– volume: 79
  start-page: 773
  issue: 11
  year: 2018
  end-page: 780
  article-title: Full‐length next‐generation sequencing of HLA class I and II genes in a cohort from Thailand
  publication-title: Hum Immunol
– volume: 71
  start-page: 627
  issue: 6
  year: 2010
  end-page: 633
  article-title: Allelic diversity and haplotype structure of HLA loci in the Chinese Han population living in the Guanzhong region of the Shaanxi province
  publication-title: Hum Immunol
– volume: 80
  start-page: 452
  issue: 5
  year: 2012
  end-page: 461
  article-title: Distinct HLA allele and haplotype distributions in four ethnic groups of China
  publication-title: Tissue Antigens
– volume: 49
  start-page: 49
  issue: 1
  year: 1964
  end-page: 67
  article-title: The interaction of selection and linkage. I general considerations; heterotic models
  publication-title: Genetics
– volume: 91
  start-page: 175
  issue: 3
  year: 2018
  end-page: 186
  article-title: Next generation sequencing characterizes the extent of HLA diversity in an Argentinian registry population
  publication-title: HLA
– volume: 69
  start-page: 192
  issue: Suppl 1
  year: 2007
  end-page: 197
  article-title: PyPop update ‐ A software pipeline for large‐scale multilocus population genomics
  publication-title: Tissue Antigens
– volume: 69
  start-page: 443
  issue: 7
  year: 2008
  end-page: 464
  article-title: Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta‐analytic review of 497 population studies
  publication-title: Hum Immunol
– volume: 11
  start-page: 1
  year: 2020
  end-page: 13
  article-title: HLA‐A, ‐B, ‐C, ‐DRB1, ‐DQB1, and ‐DPB1 allele and haplotype frequencies of 28,927 Saudi stem cell donors typed by next‐generation sequencing
  publication-title: Front Immunol
– volume: 52
  start-page: 1931
  issue: 6
  year: 2020
  end-page: 1936
  article-title: Antibody‐mediated rejection due to donor‐specific HLA‐DQB1 and DQA1 antibodies after kidney transplantation: a case report
  publication-title: Transplant Proc
– volume: 96
  start-page: 1065
  issue: 12
  year: 2013
  end-page: 1072
  article-title: HLA‐DQ barrier: effects on cPRA calculations
  publication-title: Transplantation
– volume: 13
  issue: 8
  year: 2017
  article-title: HLA class I haplotype diversity is consistent with selection for frequent existing haplotypes
  publication-title: PLoS Comput Biol
– ident: e_1_2_8_30_1
  doi: 10.1016/j.humimm.2014.04.001
– ident: e_1_2_8_15_1
  doi: 10.1371/journal.pone.0253619
– ident: e_1_2_8_20_1
  doi: 10.1038/s41588‐018‐0336‐0
– ident: e_1_2_8_9_1
  doi: 10.1016/j.humimm.2009.02.002
– ident: e_1_2_8_19_1
  doi: 10.1093/genetics/50.4.757
– ident: e_1_2_8_16_1
  doi: 10.1034/j.1399‐0039.2002.590604.x
– ident: e_1_2_8_17_1
  doi: 10.1111/tan.13811
– ident: e_1_2_8_37_1
  doi: 10.1371/journal.pgen.0020064
– ident: e_1_2_8_11_1
  doi: 10.1111/tri.12316
– ident: e_1_2_8_40_1
  doi: 10.1016/j.humimm.2013.06.025
– ident: e_1_2_8_8_1
  doi: 10.1111/tan.12966
– ident: e_1_2_8_32_1
  doi: 10.1111/j.1600‐6143.2009.02701.x
– ident: e_1_2_8_36_1
  doi: 10.1371/journal.pcbi.1005693
– ident: e_1_2_8_3_1
  doi: 10.3389/fgene.2020.00383
– ident: e_1_2_8_38_1
  doi: 10.1111/tan.14167
– ident: e_1_2_8_12_1
  doi: 10.1097/TP.0000000000000220
– ident: e_1_2_8_29_1
  doi: 10.1034/j.1399‐0039.2003.00089.x
– ident: e_1_2_8_25_1
  doi: 10.3389/fimmu.2020.544768
– ident: e_1_2_8_4_1
  doi: 10.1186/1479‐5876‐2‐30
– ident: e_1_2_8_24_1
  doi: 10.1111/tan.13210
– ident: e_1_2_8_6_1
  doi: 10.3343/ALM.2021.41.3.310
– ident: e_1_2_8_13_1
– ident: e_1_2_8_42_1
  doi: 10.1016/j.humimm.2010.02.012
– ident: e_1_2_8_44_1
  doi: 10.1111/iji.12067
– ident: e_1_2_8_34_1
  doi: 10.1534/g3.118.200367
– volume: 67
  issue: 1
  year: 2021
  ident: e_1_2_8_43_1
  article-title: Evaluation of LabType‐SSO HLA typing for HLA‐A, ‐B, ‐C, ‐DRB1, and‐DQB1 loci
  publication-title: Clin Lab
– ident: e_1_2_8_26_1
  doi: 10.1007/BF02300753
– ident: e_1_2_8_39_1
  doi: 10.1007/s00251‐014‐0757‐6
– ident: e_1_2_8_31_1
  doi: 10.1111/nep.12772
– ident: e_1_2_8_10_1
  doi: 10.1097/TP.0b013e3182a452a5
– ident: e_1_2_8_28_1
  doi: 10.1093/nar/gkz950
– ident: e_1_2_8_22_1
  doi: 10.1016/j.humimm.2018.09.005
– ident: e_1_2_8_18_1
  doi: 10.1111/j.1399‐0039.2006.00769.x
– ident: e_1_2_8_33_1
  doi: 10.1016/j.transproceed.2020.02.127
– ident: e_1_2_8_7_1
  doi: 10.1034/j.1399‐0039.2002.600101.x
– ident: e_1_2_8_2_1
  doi: 10.1016/j.humimm.2021.01.010
– ident: e_1_2_8_23_1
  doi: 10.1016/j.humimm.2019.12.005
– ident: e_1_2_8_27_1
  doi: 10.1086/282771
– ident: e_1_2_8_41_1
  doi: 10.1111/tan.12007
– year: 2020
  ident: e_1_2_8_14_1
  article-title: Annual report of the transplant 2019
  publication-title: Seoul: Korean Network for Organ Sharing
– ident: e_1_2_8_35_1
  doi: 10.1016/j.humimm.2008.05.001
– ident: e_1_2_8_21_1
  doi: 10.1111/tan.13358
– ident: e_1_2_8_5_1
  doi: 10.1016/j.jmoldx.2016.03.009
SSID ssib026970679
ssj0001619794
Score 2.473375
Snippet Data on HLA genotype distribution, including DQA1 and DPA1, in the Korean population are limited. We aimed to investigate the allele and haplotype frequencies...
SourceID proquest
pubmed
crossref
wiley
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 602
SubjectTerms allele frequency
Alleles
East Asian People
Gene Frequency
Haplotypes
High-Throughput Nucleotide Sequencing
Histocompatibility Antigens Class II - genetics
HLA population genetics
HLA-DRB1 Chains - genetics
Humans
Korean population
next‐generation sequencing
Title Allele and haplotype frequencies of 11 HLA loci in Koreans by next‐generation sequencing
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Ftan.14980
https://www.ncbi.nlm.nih.gov/pubmed/36719349
https://www.proquest.com/docview/2771333335
Volume 101
WOSCitedRecordID wos000940946100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVWIB
  databaseName: Wiley Online Library Full Collection 2020
  customDbUrl:
  eissn: 2059-2310
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001619794
  issn: 2059-2302
  databaseCode: DRFUL
  dateStart: 20160101
  isFulltext: true
  titleUrlDefault: https://onlinelibrary.wiley.com
  providerName: Wiley-Blackwell
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1La9tAEB4SJ4dc0pS83LRhE3LIRZDVane15GTaGkNdY0IMJhexu1olBiMFOw701p_Q35hfklk9nJg2EKhOEgyLNI-db2ZHMwBnmmbCMpEGmkodRNbYQHGuA0mtEXGktDVROWxCDgbxeKyGa3DZ_AtT9YdYJty8ZZT7tTdwbeavjByxE5q5ijFe3whRb3kLNr5ddUf9Rp1CoaRPk7ykXDBYkOVoxBBBRYDgO6x7DfnanuV6qx7qL9i5imJLN9T98F8fsAPbNfoknUpdPsKay3fhpjOdovMhOk_Jnb6fFj4tS7JZVWSNkTQpMkIp6fU7BF3fhExy8qNAsJnPiflFctzen37_uS37V3sxk7o8G53iHoy636-_9oJ65EJgGYKhwLDQ2YyLlEvjaCalRnfPnWKcOk1Td8Fix1JpEMUJ4RxH8OG44rHOKJOWUbYPrbzI3SEQxBI6RC3IVBpHOosMM1aJKJXOIqaL0jacN2xObN2P3I_FmCZNXIIMSkoGteF0SXpfNeH4F9FJI6sETcSfe-jcFYt5EkofiePF23BQCXG5DBMSIWyk8G1KWb29fnLdGZQ3n95PegRbfjx9VVr2GVoPs4X7Apv28WEynx3DuhzHx7XW4tNg-PMZTbHuOg
linkProvider Wiley-Blackwell
linkToHtml http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1La9tAEF5MXEguedAmcdI0m5BDL4Ks9qWFXkxS42DHlOKAyUXsrlaJwUjGj0Bu-Qn5jfklmdXDbWgLgeqkwzBI89j5ZjSaQehMk1RYKpJAE6kDZo0NFOc6kMQaETGlrWHFsgk5GESjkfrRQN_qf2HK-RCrgpv3jOK89g7uC9K_eTmAJ_BzFUHC3mRgRmDfzcufnZt-bU-hUNLXSX7VXCBbkMVuxBBQRQDoO6yGDfnmnhW_tyHqD9z5FsYWcaiz9X9vsI02K_yJ26XB7KCGyz6i2_ZkAuEH6yzB93o6yX1hFqezss0acmmcp5gQ3O23MQS_MR5nuJcD3Mzm2DziDA74l6fnu2KCtVc0rhq0ISx-Qjed78OLblAtXQgsBTgUGBo6m3KRcGkcSaXUEPC5U5QTp0nizmnkaCIN4DghnOMAPxxXPNIpodJSQnfRWpZnbh9hQBM6BDtIVRIxnTJDjVWCJdJZQHUsaaGvtZxjW00k94sxJnGdmYCA4kJALXS6Ip2WYzj-RnRSKysGJ_FfPnTm8uU8DqXPxeHiLbRXanHFhgoJIJYpeJpCWf_mHw_bg-Lm4P2kx2i9O7zux_2rQe8Qbfhl9WWj2We0tpgt3RH6YB8W4_nsS2W8r1mq8DY
linkToPdf http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LaxRBEC7CJogXY_C1Rk0n5OBlwJ5-TUMui3FJyLIESSB4GfqpC8vMspsI3vwJ_kZ_SarnsRpUEDKnORTFTD26vqqpqQI4NDRKx6TPDFUm4866TAthMkWdlQXXxlneLJtQ02lxdaXPN-Co_xemnQ-xLrglz2jO6-TgYeHjb16O4An9XBeYsG_ytERmAJvHH8eXk96ecqlVqpP8qrlgtqCa3Yg5oooM0XfeDRtKzT1rfndD1B-48y6MbeLQePt-b_AYHnX4k4xag9mBjVA9gU-j-RzDDzGVJ1_MYl6nwiyJy7bNGnNpUkdCKTmZjAgGvxmZVeSsRrhZrYj9Rio84H9-__G5mWCdFE26Bm0Mi0_hcvzh4v1J1i1dyBxDOJRZlgcXhfRC2UCjUgYDvgiaCRoM9eEdKwLzyiKOkzIEgfAjCC0KEylTjlH2DAZVXYUXQBBNmBztIGpfcBO5ZdZpyb0KDlEd90N428u5dN1E8rQYY172mQkKqGwENISDNemiHcPxN6L9XlklOkn68mGqUN-sylylXBwvMYTnrRbXbJhUCGK5xqdplPVv_uXFaNrcvPx_0j14cH48Lien07NdeJh21bd9Zq9gcL28Ca9hy329nq2WbzrbvQX9G--x
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Allele+and+haplotype+frequencies+of+11+HLA+loci+in+Koreans+by+next%E2%80%90generation+sequencing&rft.jtitle=HLA+%3A+immune+response+genetics&rft.au=Jung%2C+Kiwook&rft.au=Kim%2C+Jisoo+G.&rft.au=Shin%2C+Sue&rft.au=Roh%2C+Eun+Youn&rft.date=2023-06-01&rft.issn=2059-2302&rft.eissn=2059-2310&rft.volume=101&rft.issue=6&rft.spage=602&rft.epage=612&rft_id=info:doi/10.1111%2Ftan.14980&rft.externalDBID=n%2Fa&rft.externalDocID=10_1111_tan_14980
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2059-2302&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2059-2302&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2059-2302&client=summon