Astragaloside IV Mitigated Diabetic Nephropathy by Restructuring Intestinal Microflora and Ferroptosis

To investigate the underlying mechanism of Astragaloside IV (AS-IV) in ameliorating diabetic nephropathy (DN) by regulating intestinal microbiota ecology and intestinal mucosal barrier. Genetically db/db mice are used to establish DN mouse model to monitor the therapeutic effects of AS-IV and fecal...

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Bibliographic Details
Published in:	Molecular nutrition & food research Vol. 68; no. 6; p. e2300734
Main Authors:	Lyu, Xin, Zhang, Ting‐ting, Ye, Zhen, Chen, Ce
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 01.03.2024
Subjects:	Diabetes Diabetes mellitus Diabetic nephropathy Digestive system Dysbacteriosis Ecological effects Fecal microflora Ferroptosis Gastrointestinal tract Gut microbiota Intestinal microflora Intestine Microbiomes Microbiota Microorganisms Mucosa Nephropathy Permeability Renal function Transplantation intestinal microbiota ferroptosis Astragaloside IV gut-renal axis diabetic nephropathy
ISSN:	1613-4125, 1613-4133, 1613-4133
Online Access:	Get full text
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